Ignite Creation Date:
2024-10-26 @ 3:39 PM
Last Modification Date:
2024-10-26 @ 3:39 PM
Study NCT ID:
NCT06579976
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-08-17
Brief Title:
Multimodal High-frequency Ultrasound-based Study of Plaque Psoriasis Severity Index
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Multimodal High-frequency Ultrasound-based Study of Plaque Psoriasis Severity Indexa Prospective Cohort Study
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Psoriasis PsO is a common chronic relapsing inflammatory disease induced by a combination of genetic and environmental effects which seriously affects the quality of life of patientsPsoriasis Area and Severity IndexPASI score as the most common method used by clinicians to assess the severity of psoriasis and the effectiveness of treatment has the disadvantage of being subjective and superficialWe are therefore committed to establishing an objective real-time repeatable non-invasive microscopic assessment using high-frequency ultrasound This study will use high-frequency ultrasound to detect the patients lesion site and the 2cm site next to the lesion once and the study will continue to recruit for 6 months
Detailed Description:
High-frequency ultrasound HFUS with a center frequency of more than 10 MHz and a resolution of 16-158 μm The detailed detection items are epidermal thickness unit mm dermal thickness unit mm hypoechoic cord thickness between epidermis and dermis unit mm epidermal echo intensity dermal echo intensity clarity of the boundary between dermis and subcutaneous tissue detected by Grayscale ultrasound blood flow signal pcs detected by Color Doppler imaging and Power doppler imaging The 8 tests will be detected the skin lesions and 2cm beside skin lesions areaBased on the correlation between the 8 indexes and local PASI scores we will establish a model for the evaluation of psoriasis by multimodal high-frequency ultrasoundThis study will use high-frequency ultrasound to detect the patients lesion site and the 2cm site next to the lesion once and the study will continue to recruit for 6 months
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None