Ignite Creation Date:
2024-10-26 @ 3:39 PM
Last Modification Date:
2024-10-26 @ 3:39 PM
Study NCT ID:
NCT06575569
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-08-20
Brief Title:
Effect of HIIT on Cardiopulmonary Function After PCI in Patients With Coronary Heart Disease
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Effect of High-intensity Intermittent Rehabilitation Training on Cardiopulmonary Function After PCI in Patients With Coronary Heart Disease
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Both the gut microbiome and exercise are closely related to human health but the understanding of the effect of high-intensity interval training HIIT on cardiopulmonary function and human intestinal flora is still further study
Detailed Description:
As one of the most causes mortality all over the world coronary heart disease CHD contributes to about 178 billion in Europe 036 all deaths in the United States and over 110 million individuals worldwide each year which has been a heavy burden on health expenditure The treatment ways of CHD mainly include life way drugs and percutaneous coronary intervention PCI Even though in past decades PCI technique has developed rapidly and today is a main treatment for patients with CHD It was reported than healthcare costs will reach 177 billion by 2024 in the United States In Europe productivity losses were 13953 per person per year because of CHD Despite the traditional treatment costs and mortality owing to CHD are still high which highlights the need for research of the relationships between CHD and systems other than the cardiovascular system and comorbidities The investigators need to search for new measures to improve traditional treatment ways of CHD With the development of high-throughput sequencing technology numbers of studies have showed that closely relationship between gut microbiota and cardiopulmonary function blood glucose lipid and cholesterol profiles and some inflammatory markers in patients with chronic disease Regulation of intestinal flora may have preventive effect on disease However the study for relationship of CHD and gut microbiota is few reports Health is a topic of common concern around the world Increasing attention to the status of CHD and finding exercise prescriptions that effectively regulate the intestinal flora may lay the foundation for the prevention and treatment of chronic diseases such as CHD
Some experiments have demonstrated that High-intensity interval training HIIT can change the diversity and metabolic capacity of gut microbiota Therefore it is necessary to conduct more studies to figure out whether exercise training could improve gut microbiota and bring benefit to human
This study will explore whether 12 weeks of HIIT can effectively change the structure of human with CHD intestinal flora so as to provide a theoretical basis for the human with CHD and exercise intervention in the treatment of intestinal flora related diseases
Some experiments have demonstrated that High-intensity interval training HIIT can change the diversity and metabolic capacity of gut microbiota Therefore it is necessary to conduct more studies to figure out whether exercise training could improve gut microbiota and bring benefit to human
This study will explore whether 12 weeks of HIIT can effectively change the structure of human with CHD intestinal flora so as to provide a theoretical basis for the human with CHD and exercise intervention in the treatment of intestinal flora related diseases
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None