Ignite Creation Date:
2024-05-05 @ 11:21 AM
Last Modification Date:
2024-10-26 @ 9:02 AM
Study NCT ID:
NCT00001961
Status:
COMPLETED
Last Update Posted:
2008-03-04
First Post:
2000-01-18
Brief Title:
MRI Evaluation of Chest Pain
Sponsor:
National Heart Lung and Blood Institute NHLBI
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
MRI Evaluation of Chest Pain Compatible With Myocardial Ischemia
Status:
COMPLETED
Status Verified Date:
2005-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study will assess the value of magnetic resonance imaging MRI in detecting heart attack and heart attack risk in patients who come to the hospital emergency room because of chest pain It will also investigate whether MRI can help predict the coronary status of patients 4 to 6 weeks and 1 year after emergency room admission
Patients who come to the emergency room of Suburban Hospital in Bethesda MD because of chest pain may be asked to enroll in this study if they have not been diagnosed as having a heart attack Participating patients will undergo a MRI scan as soon as emergency room doctors determine they are in stable condition For this procedure the patient lies on a table that slides into the MRI scanner-a large tubular machine with a magnetic field During the scan a contrast material is injected into the vein This material brightens the image of the heart so that the blood flow can be seen The scan will show if there are areas of heart muscle that received insufficient blood flow A second scan will be done within 72 hours to look for coronary artery blockage that may require treatment Patients will be followed by telephone 4 to 8 weeks after the scans and again 1 year after the scans to ask about any significant medical problems that may have occurred during those time periods
This study will provide information that may improve emergency treatment of patients with acute chest pain by clarifying which patients require immediate medical treatment which should be admitted to the hospital for further evaluation and which may safely be discharged from the hospital
Patients who come to the emergency room of Suburban Hospital in Bethesda MD because of chest pain may be asked to enroll in this study if they have not been diagnosed as having a heart attack Participating patients will undergo a MRI scan as soon as emergency room doctors determine they are in stable condition For this procedure the patient lies on a table that slides into the MRI scanner-a large tubular machine with a magnetic field During the scan a contrast material is injected into the vein This material brightens the image of the heart so that the blood flow can be seen The scan will show if there are areas of heart muscle that received insufficient blood flow A second scan will be done within 72 hours to look for coronary artery blockage that may require treatment Patients will be followed by telephone 4 to 8 weeks after the scans and again 1 year after the scans to ask about any significant medical problems that may have occurred during those time periods
This study will provide information that may improve emergency treatment of patients with acute chest pain by clarifying which patients require immediate medical treatment which should be admitted to the hospital for further evaluation and which may safely be discharged from the hospital
Detailed Description:
Coronary artery disease remains the leading cause of death in the United States and results in high diagnostic and therapeutic costs The overall costs associated with the care of patients with cardiovascular disease is projected to be 2865 billion Although MRI is a relatively expensive technology this methodology can provide all the noninvasive diagnostic testing necessary to evaluate and triage patients with coronary artery disease This one stop shop has the potential to lower overall testing on this important patient population and better delineate which patients require intervention Beyond reproducing the results of existing diagnostic tests MRI has unique abilities to characterize myocardial tissue adding information in the assessment of these patients that is not attainable by currently available methodologies This study will examine the hypothesis that MRI assessment of regional LV function resting myocardial perfusion and myocardial tissue characteristics can accurately detect a higher fraction of patients with acute myocardial infarction than is possible with the ECG performed in the emergency department
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 00-H-0025 | None | None | None |