Ignite Creation Date:
2024-10-26 @ 3:39 PM
Last Modification Date:
2024-10-26 @ 3:39 PM
Study NCT ID:
NCT06574945
Status:
COMPLETED
Last Update Posted:
None
First Post:
2024-08-20
Brief Title:
Anesthesia for Loop Electrosurgical Excision Procedure LEEP
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Efficacy and Safety of Propofol in Combination With Different Esketamine Doses for Anesthesia During Loop Electrosurgical Excision Procedure
Status:
COMPLETED
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
ESKLEEP
Brief Summary:
The goal of this prospective randomized controlled study study is to investigate the efficacy and safety of propofol combined with different doses of esketamine ESK for anesthesia during loop electrosurgical excision procedure LEEPNinety female patients undergoing LEEP were randomly allocated to three groupsIt aims to answer 1The effect of esketamine combined with propofol in respiration circulation etcduring LEEP 2The appropriate dosage of esketamine when combined with propofol in LEEP anesthesia
Detailed Description:
To investigate the efficacy and safety of propofol combined with different doses of esketamine ESK for anesthesia during loop electrosurgical excision procedure LEEP Ninety female patients undergoing LEEP were randomly allocated to three groups group P 2 mgkg propofol saline group propofol esketaminePK1 15 mgkg propofol 05 mgkg ESK and group PK2 15 mgkg propofol 025 mgkg ESK Parameters including mean arterial pressure MAP heart rate HR respiratory rate RR oxygen saturation SPO2 and venous carbon dioxide PvCO2 were recorded Additionally the need for supplemental propofol jaw thrust maneuver or ventilation postoperative awakening time and adverse reactions were assessed
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None