Ignite Creation Date:
2024-10-26 @ 3:38 PM
Last Modification Date:
2024-10-26 @ 3:38 PM
Study NCT ID:
NCT06573658
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-07-30
Brief Title:
Neurophysiological Changes After Perturbation-based Training in Older Adults
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Short-term Neurophysiological Changes After a Perturbation-based Training in Community-dwelling Older Adults A Pilot Study
Status:
RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This is an assessor-blinded neurophysiological study Participants will be randomly assigned to perturbation-based training PBT or active control Neurophysiological changes in the brain following PBT compared to control will be investigated
Detailed Description:
A total of 88 participants will be randomly assigned to two groups receiving perturbation-based training PBT or active control Written informed consent will be obtained from participants before baseline assessment The study will be reported and conducted in line with the CONSORT statement Participants will be recruited via convenient sampling in the local community Both groups will receive two sessions of treadmill walking at their comfortable speed Perturbations will be induced during the treadmill walking only for the PBT group As informed from previous literature two sessions of PBT could have improved postural stability for up to 15 years Between-group differences in behavioral and MRI findings will be examined before and after training to identify training-induced changes in postural stability and structures and functional connectivities in the brain Retention of the changes in the postural stability will be assessed four months after the training period Incidents of falls will be followed up for 12 months after training
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None