Ignite Creation Date:
2024-10-26 @ 3:38 PM
Last Modification Date:
2024-10-26 @ 3:38 PM
Study NCT ID:
NCT06571474
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-08-22
Brief Title:
Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity ATM
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity-Associated Diseases
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
ATM
Brief Summary:
The goal of this study is to evaluate the role of transcription factor EB TFEB in adipose fat tissue macrophages ATM in regulating adipose tissue and systemic metabolic function in obesity The investigators will assess the differences in ATM lipid metabolism in people with metabolically abnormal obesity and lean individuals
Both groups will have
screening visit
imaging body composition testing - dual-energy x-ray absorptiometry DEXA scans magnetic resonance imaging MRI and magnetic resonance spectroscopy MRS scans
Overnight visit with intravenous infusion IV muscle and fat tissue biopsies
Both groups will have
screening visit
imaging body composition testing - dual-energy x-ray absorptiometry DEXA scans magnetic resonance imaging MRI and magnetic resonance spectroscopy MRS scans
Overnight visit with intravenous infusion IV muscle and fat tissue biopsies
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None