Ignite Creation Date:
2024-10-26 @ 3:38 PM
Last Modification Date:
2024-10-26 @ 3:38 PM
Study NCT ID:
NCT06570356
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
None
First Post:
2024-08-20
Brief Title:
Assessment of Depression Levels in Elderly Patients With an Orthopedic Fracture Compared to Patients After a Stroke
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Assessment of Depression Levels in Elderly Patients With an Orthopedic Fracture Compared to Patients After a Stroke
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Depression is common among elderly patients hospitalized due to acute conditions like strokes or osteoporotic fractures It has significant impacts on quality of life hospitalization rates and mortality Although studies have explored depression and its assessment most focus on non-geriatric or ambulatory populations This study examined depressive symptoms in elderly patients after a stroke or fracture We assessed all patients for depression symptoms using the validated Geriatric Depression Scale - 15 item GDS-15 and searched for contributing factors in each condition
Detailed Description:
Depression is a common condition among elderly patients hospitalized due to acute events and has both short-term and long-term prognostic impacts including reduced quality of life recurrent hospitalizations and even mortality Numerous studies have examined the effects of depression and the ability to assess it but most have been conducted in non-geriatric populations and in ambulatory patients It remains unclear whether different acute conditions are associated with distinct risk factors for depressive symptoms and whether depressive symptoms may have varying impacts across different acute conditions In this study we examined depressive symptoms in two groups of elderly patients-those with stroke and those with osteoporotic fractures These are two common acute conditions in the geriatric population both with significant implications for patient function and the incidence of depression
Patients were recruited from a large geriatric hospital all patients were capable of signing consent forms At the beginning of their hospitalization all patients will undergo a standardized depression screening test GDS-15 and additional data will be collected from computerized medical records including baseline data and the Functional Independence Measure FIM at the beginning and end of rehabilitation Statistical analyses including univariate analyses and multivariate regression will be conducted to identify variables associated with depressive symptoms Linear regression models will be constructed for each group based on the variables significantly associated with depression to assess the risk of depression according to the identified risk factors To evaluate the risk of depression according to the models and assess the predicted GDS values ability to classify participants with or without depression ROC curves will be used and AUC will be calculated
Patients were recruited from a large geriatric hospital all patients were capable of signing consent forms At the beginning of their hospitalization all patients will undergo a standardized depression screening test GDS-15 and additional data will be collected from computerized medical records including baseline data and the Functional Independence Measure FIM at the beginning and end of rehabilitation Statistical analyses including univariate analyses and multivariate regression will be conducted to identify variables associated with depressive symptoms Linear regression models will be constructed for each group based on the variables significantly associated with depression to assess the risk of depression according to the identified risk factors To evaluate the risk of depression according to the models and assess the predicted GDS values ability to classify participants with or without depression ROC curves will be used and AUC will be calculated
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None