Ignite Creation Date:
2024-10-26 @ 3:38 PM
Last Modification Date:
2024-10-26 @ 3:38 PM
Study NCT ID:
NCT06567431
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-03-18
Brief Title:
Blood And Tears in Alzheimers Disease
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Examination of Alzheimers Disease Biomarkers in Tears and Dry Blood Spots
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
BAT-AD
Brief Summary:
This study aims to investigate whether biomarkers of Alzheimers disease can be found in tearfluid as well as dried bloodspots in patients with Alzheimers disease other dementia diagnoses compared to controls
Detailed Description:
Participants under investigation of a neurodegenerative disease who have a planned lumbar puncture in the Memory clinic will be invited to this study On the same day of the lumbar puncture tear fluid and dry blod spots will be collected
Tear fluid is collected using Shirmers test Dried blood spots are obtained by a small prick in the finger with a lancet The blood droplet is transferred onto a special piece of filter paper where it dries
As a sub-study participants who have provided written consent specifically for this purpose will repeat the test with dried blood spots at home one week after participating in the study The samples are submitted to the Memory Clinic at the participants next scheduled appointment
Tear fluid dried blood spots as well as blood and cerebrospinal fluid will be examined for AD-related pathology
Tear fluid is collected using Shirmers test Dried blood spots are obtained by a small prick in the finger with a lancet The blood droplet is transferred onto a special piece of filter paper where it dries
As a sub-study participants who have provided written consent specifically for this purpose will repeat the test with dried blood spots at home one week after participating in the study The samples are submitted to the Memory Clinic at the participants next scheduled appointment
Tear fluid dried blood spots as well as blood and cerebrospinal fluid will be examined for AD-related pathology
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None