Ignite Creation Date:
2024-10-26 @ 3:38 PM
Last Modification Date:
2024-10-26 @ 3:38 PM
Study NCT ID:
NCT06566651
Status:
RECRUITING
Last Update Posted:
None
First Post:
2023-11-28
Brief Title:
Emotion Processing Among Patients With ALS
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Emotion and Interoception Processing in ALS
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this observational study is to learn about the emotional perception in people with ALS disease compared to people with other neuromuscular disease and healthy controls The main questions it aims to answer are
How people with ALS judge happy and angry faces and what their insight into these judgements are like
How their autonomic responses differ from the other two test group Participants will asked to judge if a face presents a happy emotion or angry emotion
Researchers will compare the ALS group responses with neuromuscular diseases group and healthy control group responses to see if the ALS group judge more happy faces than angry
How people with ALS judge happy and angry faces and what their insight into these judgements are like
How their autonomic responses differ from the other two test group Participants will asked to judge if a face presents a happy emotion or angry emotion
Researchers will compare the ALS group responses with neuromuscular diseases group and healthy control group responses to see if the ALS group judge more happy faces than angry
Detailed Description:
Mild cognitive and behavioral changes occur in 35 of ALS patients and 10-15 of patients meet the criteria for FTD1-4 Recent research suggests changes in emotional perception and social cognition are a part of the neuropsychological changes in ALS possibly associated with cognitive and behavioral symptoms seen in ALS-FTD5-9
The aim of this project is to investigate emotional perception in ALS patients compared to healthy controls and patients with other neuromuscular diseases that do not affect the central nervous system We use a simple emotion discrimination task to evaluate emotional bias and metacognition of emotion discrimination Moreover this project aims to explore the correlation between emotion perception and autonomic reactivity in ALS patients by recording heart rate frequency and respiration frequency during the EDT
The project will contribute with deeper insights to the neuropsychological changes in ALS patients and the opportunity to quantify these changes Thereby the project will add new perspectives to the discussion of how we evaluate socio-emotional aspects of ALS in both clinical decision-making guidance of relatives and future research
The aim of this project is to investigate emotional perception in ALS patients compared to healthy controls and patients with other neuromuscular diseases that do not affect the central nervous system We use a simple emotion discrimination task to evaluate emotional bias and metacognition of emotion discrimination Moreover this project aims to explore the correlation between emotion perception and autonomic reactivity in ALS patients by recording heart rate frequency and respiration frequency during the EDT
The project will contribute with deeper insights to the neuropsychological changes in ALS patients and the opportunity to quantify these changes Thereby the project will add new perspectives to the discussion of how we evaluate socio-emotional aspects of ALS in both clinical decision-making guidance of relatives and future research
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None