Ignite Creation Date:
2024-10-26 @ 3:38 PM
Last Modification Date:
2024-10-26 @ 3:38 PM
Study NCT ID:
NCT06566625
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-07-02
Brief Title:
Cardiac MRI Prior to Invasive Coronary Angiography in Patients With Suspected Non-ST-Elevation Myocardial Infarction
Sponsor:
None
Organization:
None
Study Overview
Official Title:
The Karolinska Pilot Study for Cardiac Magnetic Resonance Imaging Prior to Invasive Coronary Angiography in Patients With Suspected Non-ST-Elevation Myocardial Infarction
Status:
RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
KaPSICA-CMR
Brief Summary:
Patients with a suspected myocardial infarction are subdivided into ST-elevation and non-ST-elevation myocardial infarctions STEMI and NSTEMI respectively using an ECG While patients with STEMI are urgently referred to a cath lab patients with NSTEMI usually undergo a planned invasive coronary angiography ICA anywhere from 24-72 hours after arriving to the hospital When an invasive coronary angiography can not explain the cause of a myocardial infarction an MRI of the heart a CMR is often done as a follow-up investigation
A growing body of evidence suggests that performing a CMR before the planned ICA can provide an accurate diagnosis and defer the need for an ICA in many of these patients with NSTEMI
A growing body of evidence suggests that performing a CMR before the planned ICA can provide an accurate diagnosis and defer the need for an ICA in many of these patients with NSTEMI
Detailed Description:
KaPSICA-CMR is an observational pilot study at the Karolinska University Hospital which aims to validate in a Swedish healthcare setting the potentials of a CMR-first approach in patients with suspected NSTEMI We plan on including 150 patients both with n50 and without n100 previous myocardial infarction In addition to a standard clinical CMR protocol the study will test novel CMR techniques such as magnetic resonance angiography and magnetic resonance fingerprinting sequences in this cohort Patients will be recruited at both the Solna- and Huddinge sites of the hospital and include patients referred to ICA from the Visby- and Södertälje hospitals The findings on the CMR will be blinded to treating physicians with exceptions for unexpected adverse findings In the event that a CMR would be indicated in line with clinical practice the CMR findings are unblinded
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None