Ignite Creation Date:
2024-10-26 @ 3:38 PM
Last Modification Date:
2024-10-26 @ 3:38 PM
Study NCT ID:
NCT06562855
Status:
AVAILABLE
Last Update Posted:
None
First Post:
2024-05-13
Brief Title:
Tension-Type Headache Gene Expression and Methylation
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Gene Expression-methylation Profiling
Status:
AVAILABLE
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
TTH
Brief Summary:
Tension-type headache TTH refers to pain radiating from the forehead to the back of the head as a bilateral band It often occurs without warning and spreads to the neck muscles Patients describe it as tension pressure or dull pain It is usually triggered by stress The complexity of the processes is the biggest difficulty in diagnosing and treating TTH Although there are genetic connections there are no single responsible genes
Detailed Description:
130 TTH patients and 117 healthy controls were included in the study Serum markers of the patients were measured WNT5A responsible for the Wnt-B catenin signaling pathway and its receptor FZD3 were examined in the pathogenesis of TTH Expression changes and methylation profiles of genes were obtained Genetic and serum parameters were compared Diagnostic powers were determined by ROC analyses
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?: