Ignite Creation Date:
2024-10-26 @ 3:38 PM
Last Modification Date:
2024-10-26 @ 3:38 PM
Study NCT ID:
NCT06561477
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-08-09
Brief Title:
Role of ICCO Score in Predicting Outcome in ICU Patients
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Study of the Validity of Intensive Care Cirrhosis Outcome Score ICCO in Predicting Outcome in Cirrhotic Patients Admitted to Intensive Care Unit
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study aims at calculating a specific score to cirrhotic patients admitted at ICU ICCO score and use this score to predict mortality and outcome for admitted patients
Detailed Description:
Liver cirrhosis is the final stage of chronic liver disease It is characterized by an irreversible replacement of liver parenchyma with fibrotic tissue and regenerative nodules The major causes of cirrhosis include hepatitis B virus and hepatitis C virus infection alcohol-associated liver disease ALD and non-alcoholic fatty liver disease NAFLD
The prognosis of cirrhotic patients admitted to the ICU remains poor It was reported that the mortality rate of patients with cirrhosis admitted to an intensive care unit ICU due to organ dysfunction ranges from 34 to 69 depending on the cause of admission the presence of organ failure OF and the severity of the underlying liver disease
Several prognostic scoring systems have been used to assess patients with cirrhosis admitted to the ICU general ICU mortality risk scores such as the Sequential Organ Failure Assessment SOFA score and the Acute Physiology and Chronic Health Evaluation II APACHE II score other liver specific scores such as Model of end stage liver disease MELD score
These scores can be calculated immediately upon admission to the ICU first 24 h or during the first days of hospitalization leading to an evolutionary assessment over this short period of time
Intensive care cirrhotic outcome ICCO score is a new score that was introduced to predict mortality and ICU outcome in cirrhotic patients admitted to the ICU with limited studies that test the validity of the score and compare it with the other well-known ICU scores
In clinical practice it remains controversial to determine which score is better at predicting overall mortality this is due to that Each score is calculated according to its own criteria and only data obtained within the first 24 hours of the first ICU admittance is used
In this study investigators will test the validity of ICCO score and compare it with other different ICU scores to find out the most useful score in early prediction of ICU outcome for cirrhotic patients
The prognosis of cirrhotic patients admitted to the ICU remains poor It was reported that the mortality rate of patients with cirrhosis admitted to an intensive care unit ICU due to organ dysfunction ranges from 34 to 69 depending on the cause of admission the presence of organ failure OF and the severity of the underlying liver disease
Several prognostic scoring systems have been used to assess patients with cirrhosis admitted to the ICU general ICU mortality risk scores such as the Sequential Organ Failure Assessment SOFA score and the Acute Physiology and Chronic Health Evaluation II APACHE II score other liver specific scores such as Model of end stage liver disease MELD score
These scores can be calculated immediately upon admission to the ICU first 24 h or during the first days of hospitalization leading to an evolutionary assessment over this short period of time
Intensive care cirrhotic outcome ICCO score is a new score that was introduced to predict mortality and ICU outcome in cirrhotic patients admitted to the ICU with limited studies that test the validity of the score and compare it with the other well-known ICU scores
In clinical practice it remains controversial to determine which score is better at predicting overall mortality this is due to that Each score is calculated according to its own criteria and only data obtained within the first 24 hours of the first ICU admittance is used
In this study investigators will test the validity of ICCO score and compare it with other different ICU scores to find out the most useful score in early prediction of ICU outcome for cirrhotic patients
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None