Ignite Creation Date:
2024-10-26 @ 3:38 PM
Last Modification Date:
2024-10-26 @ 3:38 PM
Study NCT ID:
NCT06559410
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-08-12
Brief Title:
Convulsions in Neonates With Congenital Heart Diseases
Sponsor:
None
Organization:
None
Study Overview
Official Title:
A Descriptive Study on Convulsions in Neonates With Congenital Heart Diseases at Assiut University Children Hospital
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
analyze the etiology electroencephalographic EEG findings neuroimaging and neurological sequalae of newborns with congenital heart disease who were presented with seizures during their neonatal intensive care unit admission
Detailed Description:
Neonatal seizures are a commonly encountered neurologic condition in neonates They are defined as the occurrence of sudden paroxysmal abnormal alteration of electrographic activity at any point from birth to the end of the neonatal period During this period the neonatal brain is developmentally immature Thus neonatal seizures have unique pathophysiology and electrographic findings resulting in clinical manifestations that can be different and more difficult to identify when compared to older age groups
Neonatal seizures are paroxysmal repetitive and stereotypical events They are usually clinically subtle inconspicuous and difficult to recognize from the normal behaviors of the inter-ictal periods or physiological phenomena There is no recognizable post-ictal state The most widely used scheme is of five main types of neonatal seizure
Subtle seizures 50
Tonic seizures 5
Clonic seizures 25
Myoclonic seizures 20
Non-paroxysmal repetitive behaviors Neonates with congenital heart disease have a high risk of cerebral lesions seizures and neurological impairment By congenital heart disease we refer to the group of congenital malformations present at birth that include cyanotic as well as non-cyanotic cardiac lesions
Neonatal seizures are the most common clinical expression of central nervous system dysfunction in newborns and one of the most frequent neurological emergencies during this stage of life They are usually the first sign of neurological involvement and an indicator of the risk of mortality and or neurological sequelae
Neonatal seizures are paroxysmal repetitive and stereotypical events They are usually clinically subtle inconspicuous and difficult to recognize from the normal behaviors of the inter-ictal periods or physiological phenomena There is no recognizable post-ictal state The most widely used scheme is of five main types of neonatal seizure
Subtle seizures 50
Tonic seizures 5
Clonic seizures 25
Myoclonic seizures 20
Non-paroxysmal repetitive behaviors Neonates with congenital heart disease have a high risk of cerebral lesions seizures and neurological impairment By congenital heart disease we refer to the group of congenital malformations present at birth that include cyanotic as well as non-cyanotic cardiac lesions
Neonatal seizures are the most common clinical expression of central nervous system dysfunction in newborns and one of the most frequent neurological emergencies during this stage of life They are usually the first sign of neurological involvement and an indicator of the risk of mortality and or neurological sequelae
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None