Ignite Creation Date:
2024-10-26 @ 3:37 PM
Last Modification Date:
2024-10-26 @ 3:37 PM
Study NCT ID:
NCT06542263
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-08-04
Brief Title:
Clinical Study on the Effect of CPAP on AF Recurrence After Catheter Ablation in Patients With AF and OSA
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Clinical Study on the Effect of Continuous Positive Airway Pressure Ventilation on Atrial Fibrillation Recurrence After Catheter Ablation in Patients With Atrial Fibrillation and Obstructive Sleep Apnea
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Atrial fibrillation AF is the most common sustained arrhythmia in clinical practice significantly increasing the risks of death stroke heart failure cognitive impairment and dementia thus severely impacting patients quality of life However for AF patients with concomitant cardiovascular risk factors particularly those with obstructive sleep apnea OSA the success rate of catheter ablation is significantly reduced Continuous positive airway pressure CPAP is currently an effective treatment for OSA effectively correcting nocturnal intermittent hypoxia and fragmented sleep caused by OSA However the effect of CPAP therapy on AF recurrence in patients with OSA undergoing catheter ablation remains controversial Faced with conflicting research findings our team recently conducted a meta-analysis registration number CRD42023398588 to assess the impact of CPAP on AF recurrence post catheter ablation in patients with AF and OSA suggesting that CPAP significantly reduces AF recurrence post catheter ablation RR 058 P 001 However considering the limited number of included studies potential bias risks and confounding factors our meta-analysis results await further confirmation through real-world studies by our team Therefore our team plans to conduct further research on the impact of CPAP on AF recurrence post catheter ablation in patients with moderate to severe OSA aiming to provide clinical guidance for the treatment of AF in patients with moderate to severe OSA
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None