Ignite Creation Date:
2024-10-26 @ 3:37 PM
Last Modification Date:
2024-10-26 @ 3:37 PM
Study NCT ID:
NCT06542094
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-08-03
Brief Title:
Identifying Local Field Potential Biomarkers for Treatment-Resistant Major Depression With Deep Brain Stimulation
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Identifying Local Field Potential Biomarkers for Treatment-Resistant Major Depression With Deep Brain Stimulation
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Major depressive disorder MDD is a complex and severe mental illness characterized by multiple symptoms and is a leading cause of non-fatal health loss Despite this approximately 30 of patients do not respond to standard pharmacological or psychological treatments Currently we lack objective brain-based biomarkers to differentiate between natural mood fluctuations and situations requiring intervention To address this issue we employed a novel electrophysiology recording device and applied deep brain stimulation DBS to 12 MDD patients Our study aims to use long-term invasive neural signal collection and machine learning techniques to reveal the complex relationship between these signals and depressive symptoms By applying advanced machine learning algorithms our goal is to establish highly accurate prediction models to identify biomarkers associated with the occurrence and progression of depression The research will focus on the spatiotemporal features of neural signals and build personalized depression decoding models based on individual differences through the integration and analysis of large-scale data By delving into the information contained in neural signals we hope to contribute to the development of personalized treatment approaches for depression
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None