Ignite Creation Date:
2024-10-26 @ 3:37 PM
Last Modification Date:
2024-10-26 @ 3:37 PM
Study NCT ID:
NCT06540755
Status:
COMPLETED
Last Update Posted:
None
First Post:
2024-08-02
Brief Title:
Analysis of Pregnancy-Associated Plasma Protein-A and Interleukin-6 Gene Polymorphisms in Patients With Periodontitis
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Analysis of Pregnancy-Associated Plasma Protein-A and Interleukin-6 Gene Polymorphisms in Patients With Periodontitis
Status:
COMPLETED
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this study is to evaluate the relationship between pregnancy associated plasma protein-A PAPP-A and interleukin-6 IL-6 gene polymorphisms and stage 3 grade B and C S3GBC periodontitis and to compare periodontitis patients with healthy individuals
Detailed Description:
A total of 226 systemically healthy subjects consisted of 112 S3GBC periodontitis patients P group and 114 periodontally healthy individuals H group were included in our study Clinical and demographic data were recorded Genomic deoxyribonucleic acid DNA molecules were obtained from peripheral blood Genotype for IL-6 rs1800795 and PAPP-A rs7020782 polymorphisms were determined using real-time polymerase chain reaction with allele-specific probes The genotypic or allelic distributions of PAPP-A and IL-6 gene polymorphisms were similar between groups p005 Our finding suggests that there is no relationship between PAPP-A and IL-6 gene polymorphismS and S3GBC periodontitis furthermore no difference was detected between periodontitis patients and healthy individuals regarding this gene polymorphism
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None