Ignite Creation Date:
2024-10-26 @ 3:37 PM
Last Modification Date:
2024-10-26 @ 3:37 PM
Study NCT ID:
NCT06540287
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-07-26
Brief Title:
Molecular Optimization Via Exercise MOVE
Sponsor:
None
Organization:
None
Study Overview
Official Title:
An Observational Study of Aging Biomarkers in Older Elite Athletes Compared to Non-exercising Healthy Older Adults
Status:
RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study is to investigate characteristics of muscle blood and urine samples from older adults ages 65-80 who are either sedentary or athletes performing at an elite level for their age This observational study will include bio-specimen collection as well as physical and cognitive function testing and body composition
Detailed Description:
The study will enroll a total of 80 subjects-20 of each gender for each cohort Participation in the study involves 3 visits that must take place within 12 weeks Optional l follow up visits may be completed at 12- and 24- months after completion of the main study
The first visit is a screening and enrollment visit At this visit informed consent will be obtained and a detailed medical history screening blood sample collected and physical assessment will be performed including but not limited to vital signs resting ECG body composition Additionally an exercise history interview will be performed to assess for cohort eligibility Participants will be familiarized with testing equipment during the screening visit and will perform the Astrand-Rhyming submaximal bicycle test A short physical function testing battery will be performed including the short physical performance battery 6 minute walk test grip strength 1 rep max leg press and leg press fatigue testing
The second visit will include maximal exercise testing quality of life assessment and cognitive function testing Participants will be allocated into their cohort at this visit
The third visit will include thigh muscle sample collection via needle biopsy and blood sample collection
The first visit is a screening and enrollment visit At this visit informed consent will be obtained and a detailed medical history screening blood sample collected and physical assessment will be performed including but not limited to vital signs resting ECG body composition Additionally an exercise history interview will be performed to assess for cohort eligibility Participants will be familiarized with testing equipment during the screening visit and will perform the Astrand-Rhyming submaximal bicycle test A short physical function testing battery will be performed including the short physical performance battery 6 minute walk test grip strength 1 rep max leg press and leg press fatigue testing
The second visit will include maximal exercise testing quality of life assessment and cognitive function testing Participants will be allocated into their cohort at this visit
The third visit will include thigh muscle sample collection via needle biopsy and blood sample collection
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None