Ignite Creation Date:
2024-10-26 @ 3:37 PM
Last Modification Date:
2024-10-26 @ 3:37 PM
Study NCT ID:
NCT06539611
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-07-29
Brief Title:
Prospective Cohort Study of a Population at Risk of Psychotic Transition
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Prospective Cohort Study of a Population at Risk of Psychotic Transition
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
EPEDIP
Brief Summary:
In psychiatry insight is the patients awareness of his or her disorder or symptom Lack of insight also seems to be associated with the presence of anxiety-depressive symptoms
There are several forms of insight
clinical insight which is the perception of suffering from a given pathology or symptoms
cognitive insight CI which is the ability to analyse or judge ones own thoughts beliefs and judgements
and the insight of cognitive disorders or the subjective perception of the cognitive alterations or cognitive symptoms presented In this study the investigators will refer to this dimension as subjective cognitive complaint SCP in order to differentiate it from cognitive insight the name of which may lead to confusion
In schizophrenic disorders there is a positive correlation between the subjective cognitive complaint SCC and certain alterations in the neurocognitive assessment including the attentional dimension There are scales for collecting SCC in psychotic disorders such as the SSTICS To date there is no scale validated specifically for the UHR population Thus the scales used STICSS SCoRS etc are validated in populations presenting a characterised psychotic state Objective impairment is measured during a neurocognitive assessment carried out by a specialised professional a clinical psychologist specialised in neuropsychology The cognitive performance of UHR patients is impaired particularly in terms of cognitive flexibility and self-perception of cognitive disorders and there may be a discrepancy between the complaint the objective disorders and their identification as disorders by the patient
Despite this discrepancy to the investigators knowledge no study to date has investigated a possible link between SCC and psychotic transition in this population Thus it is not known whether social class may be a factor in exposure to transition or whether there is a link at all between social class and risk of transition The aim of this study is to determine psychotic transition in UHR in a 30 months follow-up and to determine whether there is a link between SCC and transition
There are several forms of insight
clinical insight which is the perception of suffering from a given pathology or symptoms
cognitive insight CI which is the ability to analyse or judge ones own thoughts beliefs and judgements
and the insight of cognitive disorders or the subjective perception of the cognitive alterations or cognitive symptoms presented In this study the investigators will refer to this dimension as subjective cognitive complaint SCP in order to differentiate it from cognitive insight the name of which may lead to confusion
In schizophrenic disorders there is a positive correlation between the subjective cognitive complaint SCC and certain alterations in the neurocognitive assessment including the attentional dimension There are scales for collecting SCC in psychotic disorders such as the SSTICS To date there is no scale validated specifically for the UHR population Thus the scales used STICSS SCoRS etc are validated in populations presenting a characterised psychotic state Objective impairment is measured during a neurocognitive assessment carried out by a specialised professional a clinical psychologist specialised in neuropsychology The cognitive performance of UHR patients is impaired particularly in terms of cognitive flexibility and self-perception of cognitive disorders and there may be a discrepancy between the complaint the objective disorders and their identification as disorders by the patient
Despite this discrepancy to the investigators knowledge no study to date has investigated a possible link between SCC and psychotic transition in this population Thus it is not known whether social class may be a factor in exposure to transition or whether there is a link at all between social class and risk of transition The aim of this study is to determine psychotic transition in UHR in a 30 months follow-up and to determine whether there is a link between SCC and transition
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None