Ignite Creation Date:
2024-10-26 @ 3:36 PM
Last Modification Date:
2024-10-26 @ 3:36 PM
Study NCT ID:
NCT06537232
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-07-31
Brief Title:
Greens-Based Crossover Trial to Improve Epigenetic Aging in Adults
Sponsor:
None
Organization:
None
Study Overview
Official Title:
A Randomized Crossover-Controlled Trial Investigating the Epigenetic Impact of a Greens-Based Supplement in Adults
Status:
RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The primary purpose of this study is to assess changes in epigenetic markers of aging and physiological parameters in overweight older adults consuming a mixed greens-based supplement over a 30-day period in a randomized crossover design
Detailed Description:
Investigators will recruit 20 overweightobese but otherwise healthy participants aged 50-65 Participants will be randomized to consume the greens-based supplement each morning for the first 30 days or second 30 days of the study Usual diet physical activity and sleep patterns will be encouraged and monitored during the duration of the study
Phlebotomy will be conducted at baseline 30-day crossover and 60-day follow-up to assess DNA methylation in peripheral blood mononuclear cells Visceral and total body fat stool microbiome composition and actigraphy will also be assessed
Phlebotomy will be conducted at baseline 30-day crossover and 60-day follow-up to assess DNA methylation in peripheral blood mononuclear cells Visceral and total body fat stool microbiome composition and actigraphy will also be assessed
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None