Ignite Creation Date:
2024-10-26 @ 3:36 PM
Last Modification Date:
2024-10-26 @ 3:36 PM
Study NCT ID:
NCT06537063
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-07-31
Brief Title:
Detection of G-quadruplex DNA Methylation in Cancer
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Early Diagnosis Value of G-quadruplex DNA Methylation in Patients With Cancer
Status:
RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study aims to evaluate the early diagnosis value of G-quadruplex DNA methylation in patients with cancer
Detailed Description:
Global DNA hypomethylation is a hallmark of most cancers that occurs early during oncogenesis We would like to investigate whether cancer-specific transcription factor binding to DNA G-quadruplex drives DNA hypomethylation in cancer In this observational study we would like to clarify whether DNA hypomethylation around G-quadruplex loci in cell-free DNA could be detected in early-stage cancer patients from healthy donors with high sensitivity and specificity
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None