Ignite Creation Date:
2024-10-26 @ 3:36 PM
Last Modification Date:
2024-10-26 @ 3:36 PM
Study NCT ID:
NCT06535165
Status:
COMPLETED
Last Update Posted:
None
First Post:
2024-08-01
Brief Title:
Effect of Red Beetroot Juice Intake in Adults With Long COVID-19
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Effect of 14-day Red Beetroot Juice Intake on Physical Function Gut Microbiota Composition and Systemic Inflammation in Adults With Long COVID-19
Status:
COMPLETED
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Red beetroot juice may have positive effects on multiple pathways involved in long COVID The aim of this pilot study was to explore the impact of beetroot juice supplementation on physical function gut microbiota and systemic inflammation in adults with long-COVID
Detailed Description:
A single-center double-blind placebo-controlled randomized trial to test the effects of 14 days of beetroot juice supplementation on functional and biological outcomes in adults with long-COVID
Participants were randomized 11 to receive either daily oral supplementation with 200 mL beetroot juice or placebo for 14 days The primary endpoint was the change from baseline to day 14 in the fatigue resistance test Secondary outcomes included the distance walked on the 6-min walk test handgrip strength and flow-mediated dilation Secondary endpoints also included changes from baseline in circulating inflammatory mediators metagenomic and fecal water metabolomic profiles Partial least squares discriminant analysis PLS-DA models were built to evaluate the differences in biological variables associated with the interventions
Participants were randomized 11 to receive either daily oral supplementation with 200 mL beetroot juice or placebo for 14 days The primary endpoint was the change from baseline to day 14 in the fatigue resistance test Secondary outcomes included the distance walked on the 6-min walk test handgrip strength and flow-mediated dilation Secondary endpoints also included changes from baseline in circulating inflammatory mediators metagenomic and fecal water metabolomic profiles Partial least squares discriminant analysis PLS-DA models were built to evaluate the differences in biological variables associated with the interventions
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None