Ignite Creation Date:
2024-10-26 @ 3:36 PM
Last Modification Date:
2024-10-26 @ 3:36 PM
Study NCT ID:
NCT06534541
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-07-30
Brief Title:
Genetic Risk Parental Feeding Practices and Appetitive Traits in Early Life
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Characterizing the Relationships of Genetic Risk and Parental Coercive Feeding Practices With Appetitive Traits and Adiposity Gain Across Early Life
Status:
RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The preschool years 2-5 years of age is a critical timeframe to shape the lifetime risk of obesity While the causes of obesity are complex appetitive traits related to overeating such as high food approach and low food avoidance are robustly associated with a greater BMI among children Some children are genetically pre-disposed to expressing obesogenic appetitive traits and those traits may mediate a genetic risk for obesity Separately parental feeding practices are emerging as an important yet modifiable influence on childrens obesity risk Coercive control feeding practices such as strictly limiting a childs intake of highly palatable foods restriction and using food to control childrens negative emotions emotional feeding are believed to be detrimental for young children because they impede self-regulatory skills around eating and may increase the saliency of highly palatable foods The goal for this project is to disentangle the inter-relationships between coercive control feeding practices childrens obesogenic appetitive traits and childrens dietary intake across the preschool years to understand how coercive control feeding practices ultimately impact childrens adiposity gain over time Importantly the investigators aim to understand how those effects differ based on childrens underlying genetic risk for obesity The investigators hypothesize that parents will respond to childrens obesogenic appetitive traits by exhibiting more coercive control feeding practices restriction emotional feeding which in turn will promote future increase in obesogenic appetitive traits and overconsumption leading to excess adiposity gain among children Importantly the investigators hypothesize children with a high genetic risk for obesity will be most susceptible to the negative effects of coercive control feeding practices because food is highly salient for them The investigators will test the hypotheses among a cohort of children aged 25 years old using a longitudinal study design with repeated assessments every 6 months until children are 5 years old If successful study findings may be leveraged to develop tailored strategies to help parents support healthy eating behaviors among their young children that consider the heterogeneity in obesogenic appetitive traits among young children due to genetic risk factors
Detailed Description:
The goal for this project is to disentangle the inter-relationships between coercive control feeding practices childrens obesogenic appetitive traits and childrens dietary intake across the preschool years to understand how coercive control feeding practices ultimately impact childrens adiposity gain over time
The investigators will assess childrens genetic risk for obesity via candidate single-nucleotide polymorphisms SNPs and a polygenic risk score Importantly this novel approach expands upon previous research by including the investigators labs proven objective paradigm to measure childrens food approach and overconsumption Specifically the investigators will use eye-tracking to measure childrens attentional bias to food an objective metric of food approach The investigators also include an eating in the absence of hunger paradigm to objectively measure childrens overconsumption
The investigators will test this hypotheses among a cohort of children aged 25 years old using a longitudinal study design with repeated assessments every 6 months until children are 5 years old
The investigators will assess childrens genetic risk for obesity via candidate single-nucleotide polymorphisms SNPs and a polygenic risk score Importantly this novel approach expands upon previous research by including the investigators labs proven objective paradigm to measure childrens food approach and overconsumption Specifically the investigators will use eye-tracking to measure childrens attentional bias to food an objective metric of food approach The investigators also include an eating in the absence of hunger paradigm to objectively measure childrens overconsumption
The investigators will test this hypotheses among a cohort of children aged 25 years old using a longitudinal study design with repeated assessments every 6 months until children are 5 years old
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None