Ignite Creation Date:
2024-10-26 @ 3:36 PM
Last Modification Date:
2024-10-26 @ 3:36 PM
Study NCT ID:
NCT06529809
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-07-26
Brief Title:
Accelerated Brachytherapy Forward Chemo Radiation Therapy ABC-RT for Locally-advanced Cervical Cancer
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Accelerated Brachytherapy Forward Chemo Radiation Therapy ABC-RT for Locally-advanced Cervical Cancer
Status:
RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The standard treatment for locally advanced cervical cancer is well established as a combination of chemotherapy and radiation typically over 25-28 daily fractions with the addition of a brachytherapy boost to the primary tumor An important component to treatment efficacy is overall treatment time Prolongation of overall treatment time has been shown to lead to worse local control and overall survival thus strategies to effectively deliver radiation efficiently is required
This is a pragmatic feasibility study to determine the impact of upfront brachytherapy combined with hypofractionated external beam radiation for patients with locally advanced cervical cancer FIGO 2018 stage IB3-IVA on late gastrointestinal and genitourinary toxicity oncologic outcomes including recurrence free survival and systemic and local immune response
This is a pragmatic feasibility study to determine the impact of upfront brachytherapy combined with hypofractionated external beam radiation for patients with locally advanced cervical cancer FIGO 2018 stage IB3-IVA on late gastrointestinal and genitourinary toxicity oncologic outcomes including recurrence free survival and systemic and local immune response
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None