Ignite Creation Date:
2024-10-26 @ 3:36 PM
Last Modification Date:
2024-10-26 @ 3:36 PM
Study NCT ID:
NCT06528522
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-07-12
Brief Title:
Impact of Smoking on Salivary Interleukin IL-39 IL-41 IL-1β TNF-α Levels in Periodontal Disease
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Impact of Smoking on Salivary Inflammatory Cytokines Interleukin IL-39 IL-41 IL-1β TNF-α in Periodontal Disease
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this observational study is to evaluate if the measurement of salivary Interleukin IL-39 IL-41 IL-1Betaβ and Tumor necrosis factor-alpha TNF-α levels can aid in the early diagnosis of periodontitis in patients with varying periodontal conditions both smokers and non-smokers The main questions it aims to answer are
Can salivary IL-39 IL-41 IL-1β and TNF-α levels be used as biomarkers for the early diagnosis of periodontitis How do IL-41 and IL-39 levels correlate with smoking status in periodontal healthy and periodontitis patients Researchers will compare the salivary biomarker levels between smokers and non-smokers to see if smoking affects these levels
Participants will
Provide salivary samples for biomarker analysis Undergo a comprehensive periodontal examination to determine their periodontal status
Can salivary IL-39 IL-41 IL-1β and TNF-α levels be used as biomarkers for the early diagnosis of periodontitis How do IL-41 and IL-39 levels correlate with smoking status in periodontal healthy and periodontitis patients Researchers will compare the salivary biomarker levels between smokers and non-smokers to see if smoking affects these levels
Participants will
Provide salivary samples for biomarker analysis Undergo a comprehensive periodontal examination to determine their periodontal status
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None