Ignite Creation Date:
2024-10-26 @ 3:36 PM
Last Modification Date:
2024-10-26 @ 3:36 PM
Study NCT ID:
NCT06527989
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-07-26
Brief Title:
Prophylactic Antibiotic in Subtalar Fusion Surgery
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Prophylactic Antibiotic in Subtalar Fusion Surgery 24 Hours Versus 5 Days
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Assessment of surgical site infection when using postoperative antibiotic prophylaxis in subtalar fusion surgery 24hours versus 5 days
Detailed Description:
Infection in orthopedic surgery is one of the most dreaded complications Antibiotic prophylaxis should be utilized routinely in foot and ankle surgeries involving bone utilizing hardware and prosthetic joints
It is appropriate for the antibiotics to be administered within 60 minutes prior to surgery discontinued within 24 hours after surgery given prior to tourniquet inflation and utilized routinely in prolonged foot and ankle surgery cases
Narrow spectrum antibiotics covering Staphylococcus aureus should be utilized for prophylaxis in patients without a history of resistant infection According to American Society of Health System Pharmacists ASHP cefazolin was the most used antibiotic in preoperative prophylaxis combination of cefazolin with gentamicin was the second common regimen while 3rd generation cephalosporin were 3rd widely used antibiotics
The controversy persists in administration of antibiotics varying from a single dose to 3 doses to 5 days or 14 days In subtropical country with a hot and humid climate is a conducive environment for both Gram-positive and Gram-negative bacterial colonization of skin Therefore we need studies tailored to our environment in Egypt Prevention of SSIs is critical for the health of patients Economic efficiency Antibiotic resistance considerations In conclusion in many ways the topic of prophylactic antibiotics in elective foot and ankle surgery is an unusual one in that a relative divide exists between empirical science and common practice
It is appropriate for the antibiotics to be administered within 60 minutes prior to surgery discontinued within 24 hours after surgery given prior to tourniquet inflation and utilized routinely in prolonged foot and ankle surgery cases
Narrow spectrum antibiotics covering Staphylococcus aureus should be utilized for prophylaxis in patients without a history of resistant infection According to American Society of Health System Pharmacists ASHP cefazolin was the most used antibiotic in preoperative prophylaxis combination of cefazolin with gentamicin was the second common regimen while 3rd generation cephalosporin were 3rd widely used antibiotics
The controversy persists in administration of antibiotics varying from a single dose to 3 doses to 5 days or 14 days In subtropical country with a hot and humid climate is a conducive environment for both Gram-positive and Gram-negative bacterial colonization of skin Therefore we need studies tailored to our environment in Egypt Prevention of SSIs is critical for the health of patients Economic efficiency Antibiotic resistance considerations In conclusion in many ways the topic of prophylactic antibiotics in elective foot and ankle surgery is an unusual one in that a relative divide exists between empirical science and common practice
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None