Ignite Creation Date:
2024-10-26 @ 3:36 PM
Last Modification Date:
2024-10-26 @ 3:36 PM
Study NCT ID:
NCT06524765
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-07-11
Brief Title:
Intestinal Microbiota and Their Antibiotic Resistance Genes of ICU Health Care Workers
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Comparison of Intestinal Microbes and Their Antibiotic Resistance Genes in ICU Health Care Workers and Non-medical Professionals
Status:
RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
In this study metagenomic sequencing 10G results of stool samples from health care workers in ICU and non-medical professionals were compared to observe whether there are significant differences in community diversity structure and function of intestinal microbiota and whether there are drug resistance genes carried by intestinal microbes so as to determine whether long-term exposure to multi-pathogen environment in ICU has an impact on intestinal microbiota
Detailed Description:
The infection rate of multidrug-resistant bacteria in critically ill patients in intensive care unit ICU is high resulting in high mortality prolonged hospitalization and becoming a source of pathogen transmission The front-line medical staff engaged in ICU are constantly in contact with patients and exposed to the intensive care unit ICU environment and this high-risk contact and exposure makes many pathogenic microorganisms and their drug-resistance genes become part of the intestinal microbiota of ICU medical staff and are carried So far there have been no previous reports on the characteristics of intestinal microbiome and the drug resistance genes carried by ICU staff Therefore in this study metagenomic sequencing 10G results of stool samples from medical staff and non-medical professionals in ICU were compared to observe whether there are significant differences in community diversity structure and function of intestinal microbiota and whether there are drug resistance genes carried by intestinal microbes so as to determine whether long-term exposure to multi-pathogen environment in ICU has an impact on intestinal microbiota
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None