Ignite Creation Date:
2024-10-26 @ 3:36 PM
Last Modification Date:
2024-10-26 @ 3:36 PM
Study NCT ID:
NCT06521619
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
None
First Post:
2024-07-22
Brief Title:
Analysis of Postoperative Analgesic of Different Nerve Blocks for Total Knee Replacement Surgery
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Analysis of Postoperative Analgesic Effect and Complications Among Different Approaches of Nerve Block for Total Knee Replacement Surgery
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study is a retrospective analysis using the accumulated clinical database from 201709-202311 to analyze patients who underwent total knee arthroplasty and received nerve blocks The aim is to compare the analgesic effects incidence of nerve injury and rate of chronic pain under different nerve block techniques
Detailed Description:
Protocol title Analysis of postoperative analgesic effect and complications among different approaches of nerve block for total knee replacement surgery Objectives There is no consensus on the optimal nerve block choice for knee joint replacement Therefore the aim of this study is to conduct a retrospective analysis using data from patients who underwent total knee replacement TKR and received nerve blocks at our hospital This study will investigate the postoperative analgesic consumption duration of pain relief motor function block complications and patient satisfaction for different nerve block techniques The goal of this project is to identify the optimal nerve block choice to benefit future patients undergoing knee joint replacement
Background After undergoing total knee replacement TKR patients need rehabilitation to restore knee function and reduce postoperative adhesions However pain often prevents them from achieving this goal Clinically nerve block anesthesia is gradually becoming mainstream as it achieves intraoperative anesthesia and postoperative analgesia by infiltrating local anesthetics into the nerves supplying the knee joint According to a study by Allen et al 1998 patients receiving nerve blocks such as femoral and sciatic nerve blocks experienced better pain relief within the first 8 hours postoperatively and had a 50 reduction in total morphine consumption on the second postoperative day compared to those who received spinal anesthesia alone Carli et al 2010 found that patients who received femoral nerve blocks used less postoperative patient-controlled analgesia PCA and had better postoperative motor function recovery compared to those who received periarticular anesthetic infiltration
Currently there are various types of nerve block techniques including femoral nerve obturator nerve adductor canal nerve and sciatic nerve blocks Different nerve block techniques result in varying analgesic efficacy duration functional impact motor block and complications Sharma et al 2010 indicated that femoral nerve blocks might cause quadriceps muscle weakness and patient falls Kinghorn et al 2012 also reported that sciatic nerve blocks might result in foot drop
Study Design This study is a retrospective analysis using the accumulated clinical database from 201709-202311 to analyze patients who underwent total knee arthroplasty and received nerve blocks The aim is to compare the analgesic effects incidence of nerve injury and rate of chronic pain under different nerve block techniques
Methods A Evaluation Methods Data is collected in a patient registry called acute pain service APS which is the medical record for documenting the dose of patient controlled analgesia and side effects of PCA or nerve blocks
1 Duration of Pain Relief Ask patients when they started to feel pain duration
2 Quantitative Assessment of Analgesic Effectiveness Patients receiving nerve blocks will also use intra-venous patient-controlled analgesia PCA for 2 days postoperatively The total amount of medication used in the PCA machine over these 2 days will reflect the patients pain level
i Pain VAS score ii Motor Block Assessment The motor function of patients who received nerve blocks will be evaluated for abnormalities the day after surgery Motor block will be assessed using the Modified Bromage Motor Blockade Score c Complication Statistics Defined as conditions like foot drop quadriceps muscle weakness or any situation requiring special medical treatment
Background After undergoing total knee replacement TKR patients need rehabilitation to restore knee function and reduce postoperative adhesions However pain often prevents them from achieving this goal Clinically nerve block anesthesia is gradually becoming mainstream as it achieves intraoperative anesthesia and postoperative analgesia by infiltrating local anesthetics into the nerves supplying the knee joint According to a study by Allen et al 1998 patients receiving nerve blocks such as femoral and sciatic nerve blocks experienced better pain relief within the first 8 hours postoperatively and had a 50 reduction in total morphine consumption on the second postoperative day compared to those who received spinal anesthesia alone Carli et al 2010 found that patients who received femoral nerve blocks used less postoperative patient-controlled analgesia PCA and had better postoperative motor function recovery compared to those who received periarticular anesthetic infiltration
Currently there are various types of nerve block techniques including femoral nerve obturator nerve adductor canal nerve and sciatic nerve blocks Different nerve block techniques result in varying analgesic efficacy duration functional impact motor block and complications Sharma et al 2010 indicated that femoral nerve blocks might cause quadriceps muscle weakness and patient falls Kinghorn et al 2012 also reported that sciatic nerve blocks might result in foot drop
Study Design This study is a retrospective analysis using the accumulated clinical database from 201709-202311 to analyze patients who underwent total knee arthroplasty and received nerve blocks The aim is to compare the analgesic effects incidence of nerve injury and rate of chronic pain under different nerve block techniques
Methods A Evaluation Methods Data is collected in a patient registry called acute pain service APS which is the medical record for documenting the dose of patient controlled analgesia and side effects of PCA or nerve blocks
1 Duration of Pain Relief Ask patients when they started to feel pain duration
2 Quantitative Assessment of Analgesic Effectiveness Patients receiving nerve blocks will also use intra-venous patient-controlled analgesia PCA for 2 days postoperatively The total amount of medication used in the PCA machine over these 2 days will reflect the patients pain level
i Pain VAS score ii Motor Block Assessment The motor function of patients who received nerve blocks will be evaluated for abnormalities the day after surgery Motor block will be assessed using the Modified Bromage Motor Blockade Score c Complication Statistics Defined as conditions like foot drop quadriceps muscle weakness or any situation requiring special medical treatment
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None