Ignite Creation Date:
2024-10-26 @ 3:36 PM
Last Modification Date:
2024-10-26 @ 3:36 PM
Study NCT ID:
NCT06520384
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-07-21
Brief Title:
Radiofrequency Applications and Alcoholic Neurolysis of Genicular Nerve for the Treatment of Knee Osteoarthritic Pain
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Comparison of Radiofrequency Applications and Alcoholic Neurolysis of Genicular Nerve for the Treatment of Knee Osteoarthritic Pain A Randomized Trial
Status:
RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study aims to investigate the efficacy of radiofrequency ablation and alcoholic neurolysis of genicular nerve on alleviating pain and improving the function of advanced knee osteoarthritis patients
Detailed Description:
Knee osteoarthritis OA is a major cause of pain and disability Patients with moderate to severe knee OA often suffer from excruciating pain with chronic inflammation and reduced range of motion
Conventional treatment of knee OA includes nonpharmacologic therapies and pharmacologic therapies Analgesics low-potency opioids narcotic analgesics and nonsteroidal anti-inflammatory drugs NSAIDs are commonly used in pharmacologic therapies
Radiofrequency ablation RFA has been used for the treatment of chronic pain that has been unresponsive to conservative therapies It acts by disrupting the transmission of pain signals using thermal lesion production to interrupt nociceptive signals
The nerve block is conventionally performed by local anesthesia alone or in combination with corticosteroid Nerve ablation causes iatrogenic neural degeneration aiming only for sensory or sympathetic denervation without motor deficits The nerve ablation methods currently available are performed by either thermal ablation using RFA or chemical ablation using alcohol or phenol
Conventional treatment of knee OA includes nonpharmacologic therapies and pharmacologic therapies Analgesics low-potency opioids narcotic analgesics and nonsteroidal anti-inflammatory drugs NSAIDs are commonly used in pharmacologic therapies
Radiofrequency ablation RFA has been used for the treatment of chronic pain that has been unresponsive to conservative therapies It acts by disrupting the transmission of pain signals using thermal lesion production to interrupt nociceptive signals
The nerve block is conventionally performed by local anesthesia alone or in combination with corticosteroid Nerve ablation causes iatrogenic neural degeneration aiming only for sensory or sympathetic denervation without motor deficits The nerve ablation methods currently available are performed by either thermal ablation using RFA or chemical ablation using alcohol or phenol
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None