Ignite Creation Date:
2024-10-26 @ 3:36 PM
Last Modification Date:
2024-10-26 @ 3:36 PM
Study NCT ID:
NCT06520358
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-07-19
Brief Title:
Acute Intermittent Hypoxia to Improve Airway Protection in Chronic Traumatic Brain Injury
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Acute Intermittent Hypoxia to Improve Airway Protection in Chronic Traumatic Brain Injury
Status:
RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Acute intermittent hypoxia AIH involves 1-2min of breathing low oxygen air to stimulate neuroplasticity Animal and human studies show that AIH improves motor function after neural injury particularly when paired with task-specific training Using a double blind cross-over study we will test whether AIH and task-specific airway protection training improves airway protection more than training alone in individuals with chronic mild-moderate traumatic brain injury TBI
Detailed Description:
Recent studies have found that acute intermittent hypoxia AIH-or repetitive exposure to brief episodes of low inspired oxygen--is a promising new strategy that can help restore motor function by promoting neuroplasticity throughout the central nervous system CNS Both rodent and human studies show that motor function is further enhanced when AIH is paired with task-specific trainingrehabilitation TST Therefore this study will investigate the therapeutic potential of combining AIH with a task-specific airway protection training We propose that the combined use of AIH TST will enhance the magnitude and duration of TST training alone in individuals with chronic traumatic brain injury
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None