Ignite Creation Date:
2024-10-26 @ 3:35 PM
Last Modification Date:
2024-10-26 @ 3:35 PM
Study NCT ID:
NCT06519760
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-07-17
Brief Title:
68Ga-C1 PET CT Imaging in Clear Cell Renal Cell Carcinoma
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Evaluation of Diagnostic Value of 68Ga-C1 PET CT Imaging in Clear Cell Renal Cell Carcinoma
Status:
RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this clinical trial is to evaluate the diagnostic value of CAIX protein specific probe 68Ga-C1 in PETCT imaging in clear cell renal cell carcinoma patients It will also learn about the safety tolerability and radiation dosimetry of 68Ga-C1
Researchers will compare the diagnostic value of 68Ga-C1 PETCT and 18F-FDG PETCT in Chinese patients with indeterminate renal masses or confirmed clear cell renal cell carcinoma
Researchers will compare the diagnostic value of 68Ga-C1 PETCT and 18F-FDG PETCT in Chinese patients with indeterminate renal masses or confirmed clear cell renal cell carcinoma
Detailed Description:
Carbonic anhydrase IX CAIX is a transmembrane protein which is highly expressed in approximately 95 of clear cell renal cell carcinomas and it is closely related to tumor progression patients prognosis and treatment response Here we developed a CAIX specific small molecule probe 68Ga-C1 which has shown a good diagnostic accuracy in PETCT imaging in our preclinical mouse model of clear cell renal cell carcinoma This enables high-contrast imaging of clear cell renal carcinoma providing a new imaging method for the precise diagnosis of clear cell renal carcinoma In this clinical trail we will compare the diagnostic value of 68Ga-C1 PETCT and 18F-FDG PETCT in Chinese patients with indeterminate renal masses or confirmed clear cell renal cell carcinoma
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None