Ignite Creation Date:
2024-10-26 @ 3:35 PM
Last Modification Date:
2024-10-26 @ 3:35 PM
Study NCT ID:
NCT06513988
Status:
COMPLETED
Last Update Posted:
None
First Post:
2024-07-16
Brief Title:
Application of MI-BCI Combined With tDCS in Early Rehabilitation After Anterior Cruciate Ligament Reconstruction
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Application of MI-BCI Combined With tDCS in Early Rehabilitation After Anterior Cruciate Ligament Reconstruction Monitored by Resting-stage fMRI the First Case Report
Status:
COMPLETED
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To recover lower-limb motor function is a primary goal for rehabilitation after anterior cruciate ligament ACL reconstruction Although quantitative testing and questionnaire evaluation provide a lot of valuable information while functional magnetic resonance imaging fMRI provides a powerful method to assess functional connectivity FC involved in motor function recovery before and after receiving a novel combined rehabilitation training However our understanding of the FC changes during early rehabilitation after ACL reconstruction is partial and incomplete
Detailed Description:
ACL has become one of the most common and easily damaged knee ligaments in sports and military training affecting young and active people The extensive interest in ACL ruptures is related to the subsequent articular degeneration and severe dysfunction resulting in skeletal muscle functional limitations not only in athletics but also in daily living Thus restoring lower limb motor function and stability has become the primary goal after ACL reconstruction ACLR Moreover the newest study has indicated that increased neural activity may reflect central neuroplastic strategies to preserve motor functionality after ACLR1 Postsurgical rehabilitation guidelines for the orthopedic clinician recommended a common treatments for ACLR patients2 however because of long time consuming and poor compliance which are difficult to get patient recognition it is very urgent to find a safe effective and easy conduct and alternative therapy Transcranial direct-current stimulation tDCS is a non-invasive technique of brain stimulation that has potential for clinical utility in neurorehabilitation and could improve the lower excitability muscle strength and dynamic balance by acting on the primary motor cortex3 For another motor imagery based brain-computer interface MI-BCI based neuro rehabilitation paradigms have emerged as a novel iatrotechnics on motor function and brain function recovery4 However it is little explored whether the clinical application of MI-BCI therapy combined with tDCS could be effective for early rehabilitation after ACLR patients This case report would explore the efficacy and neuromechanism for the ACLR patient treated with MI-BCI training combined with tDCS BOLD-fMRI was performed before and after four weeks treatment
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None