Ignite Creation Date:
2024-10-26 @ 3:35 PM
Last Modification Date:
2024-10-26 @ 3:35 PM
Study NCT ID:
NCT06512519
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-07-16
Brief Title:
Second Haplo-transplantation for Graft Failure
Sponsor:
None
Organization:
None
Study Overview
Official Title:
A Multicenter Prospective Study of Second Haploidentical Transplantation for Graft Failure After the First Haploidentical Transplantation
Status:
RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Graft failure is a fatal complication following allogeneic stem cell transplantation where a second transplantation is usually required for salvage There are no recommended regimens for second transplantations for graft failure especially in the haploidentical transplant setting We recently reported encouraging outcomes using a novel method haploidentical transplantation from a different donor after conditioning with fludarabine and cyclophosphamide However the study was performed in single-center and with very small sample size Therefore it should be further validated via multicenter study In this multi-center study we aim to further evaluate the safety and efficacy of this protocol
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None