Ignite Creation Date:
2024-10-26 @ 3:35 PM
Last Modification Date:
2024-10-26 @ 3:35 PM
Study NCT ID:
NCT06505057
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-07-11
Brief Title:
Ovarian Tissue Cryopreservation and Subsequent Auto-Transplantation for Female Cancer Patients HKCH
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Ovarian Tissue Cryopreservation and Subsequent Auto-Transplantation for Female
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Ovarian tissue freezing is an ideal option for these patients as it can be performed immediately and does not need any time for ovarian stimulation We hope we can develop this service in our locality to allow more young female cancer patients to have their fertility preserved
Detailed Description:
To date transplantation of cryopreserved ovarian tissue has resulted in births of at least 130 children but data on transplantation of ovarian tissue removed before puberty are scarce
During ovarian tissue cryopreservation OTC it is possible to freeze isolated oocytes In 2003 Revel et al described for the first time oocyte isolation in children younger than 12 years with seven eight and seven oocytes isolated from the ovarian cortex of patients aged 5 8 and 10 years respectively
At this moment financial constraint is another great hindrance to fertility preservation in Hong Kong as the procedure is not cheap Cryopreservation of gametes and embryos involving assisted reproductive technology is expensive and the costs of fertility preservation impose a great burden to these cancer patients on top of the great expenses for their chemo- or radiotherapy It is almost impossible for underprivileged families
Young cancer patients may often need immediate gonadotoxic treatment for their cancer just like those with haematological cancers In these patients egg or embryo freezing is not possible as it takes at least 8-12 days time for ovarian stimulation Ovarian tissue freezing is an ideal option for these patients as it can be performed immediately and does not need any time for ovarian stimulation We hope we can develop this service in our locality to allow more young female cancer patients to have their fertility preserved
During ovarian tissue cryopreservation OTC it is possible to freeze isolated oocytes In 2003 Revel et al described for the first time oocyte isolation in children younger than 12 years with seven eight and seven oocytes isolated from the ovarian cortex of patients aged 5 8 and 10 years respectively
At this moment financial constraint is another great hindrance to fertility preservation in Hong Kong as the procedure is not cheap Cryopreservation of gametes and embryos involving assisted reproductive technology is expensive and the costs of fertility preservation impose a great burden to these cancer patients on top of the great expenses for their chemo- or radiotherapy It is almost impossible for underprivileged families
Young cancer patients may often need immediate gonadotoxic treatment for their cancer just like those with haematological cancers In these patients egg or embryo freezing is not possible as it takes at least 8-12 days time for ovarian stimulation Ovarian tissue freezing is an ideal option for these patients as it can be performed immediately and does not need any time for ovarian stimulation We hope we can develop this service in our locality to allow more young female cancer patients to have their fertility preserved
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None