Ignite Creation Date:
2024-10-25 @ 8:04 PM
Last Modification Date:
2024-10-26 @ 3:39 PM
Study NCT ID:
NCT06580249
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-08-28
Brief Title:
Efficacy and Mechanism of rTMS on the Symptoms of Pleasure Deficit in Adolescent Depression
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Efficacy and Mechanism of Repetitive Transcranial Magnetic Stimulation on the Symptoms of Pleasure Deficit in Adolescent Depression
Status:
RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
1 Primary objective to collect data on the score of pleasure deficit scale before and after repetitive transcranial magnetic stimulation treatment in adolescent depressed patients and to verify its efficacy and safety in adolescent depressed patients in combination with the changes of clinical symptoms 2 Secondary objective to explore the relevant hemodynamic mechanisms in adolescent depressed patients before and after repetitive transcranial magnetic stimulation treatment
Detailed Description:
Depression is one of the most common mental disorders among adolescents and is characterized by persistent low mood According to a global statistical report released by the World Health Organization about 350 million people worldwide are affected by depression with the adolescent population being particularly prominent Epidemiologic surveys in the Chinese region show that the prevalence of depression in adolescents is about 30 The study points out that age is one of the key factors affecting major depression Pleasure deficit a reduced capacity for the experience of pleasure or a lack of appropriate emotional responses to rewards and positive stimuli is a core symptom of depression and is considered a key internal phenotype of the illness Repetitive transcranial magnetic stimulation is a treatment for major depressive disorder that delivers a series of equally spaced pulses through repetitive TMS Studies have shown that rTMS stimulation of the dorsolateral prefrontal cortex can significantly improve symptoms of pleasure deficit Thus rTMS may be an effective treatment option for depressed patients with pleasure deficit
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None