Ignite Creation Date:
2024-10-25 @ 8:04 PM
Last Modification Date:
2024-10-26 @ 3:40 PM
Study NCT ID:
NCT06600464
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
None
First Post:
2024-09-14
Brief Title:
Ultrasound Findings of Thumb Muscles in 1st Carpometacarpal Osteoarthritis
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Is There a Relationship Between Ultrasound Findings of Thumb Muscles and Grip Strength in Addition to Pain Threshold in Thumb Carpometacarpal Osteoarthritis
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Carpometacarpal CMC joint osteoarthritis is a disorder that is estimated to affect more than one-third of postmenopausal women leading to decreased muscle strength reduced joint range of motion and painThe pathogenesis of thumb CMC osteoarthritis involves complex interactions between biomechanical forces genetic predisposition hormonal changes repetitive microtrauma and aging An important factor in the progression of carpometacarpal osteoarthritis is the loss of joint stability provided by the surrounding muscles 2 The common methods for diagnosing thumb CMC OA is plain radiographs and clinical examinations However radiographs are unable to assess the role of surrounding structures including muscles and ligaments
Ultrasound is a cost-effective radiation-free and easily applicable imaging method
Ultrasound is a cost-effective radiation-free and easily applicable imaging method
Detailed Description:
In this cross-sectional study patients with various stages of 1st carpometacarpal CMC joint osteoarthritis OA were assessed using standard radiographs based on the Modified Eaton Litter classification Postmenopausal women with clinical andor radiological evidence of 1st CMC OA will be included Group 1 In the healthy control group subjects will be matched based on age and hand dominance Group 2 Demographic information including age sex height weight body mass index BMI kgm² dominant hand and symptom duration in months will recorded Pain levels will be assessed using the Visual Analogue Scale VASThe thickness of the thenar eminence muscles longitudinal thickness of the first dorsal interosseous muscle FDI abductor pollicis brevis APB and opponens pollicis OPP was measured using musculoskeletal ultrasound Muscle strength in both hands will be evaluated using grip strength measured with a dynamometer Pressure pain threshold PPT for painful and non-painful finger joints will be assessed using a hand-held algometer
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None