Ignite Creation Date:
2024-10-25 @ 8:03 PM
Last Modification Date:
2024-10-26 @ 3:36 PM
Study NCT ID:
NCT06526780
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-07-19
Brief Title:
Bronchoscopy Versus Imaging in Diagnosis of Airway Diseases in Critically Ill Children
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Bronchoscopy Versus Imaging in Diagnosis of Airway Diseases in Critically Ill Children
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Patients with suspected airway illness often go through a diagnostic assessment that includes chest radiographs Computed tomography scans and fiber optic bronchoscopy
Detailed Description:
A correct diagnosis is necessary for effective therapy of airway illness Usually necessary for these invasive treatments The gold standard for tracheobronchial pathology identification and diagnosis is rigid or fiber optic bronchoscopy Fiber Optic is a procedure that is generally safe although it can have negative effects particularly in patients who are at greater risk Therefore it is important to continually develop and improve non-invasive procedures that enable airway examination
The laryngotracheal and bronchial airway is affected by a wide range of diseases and imaging is essential for assessing these anomalies The location scope and type of these lesions may be determined with great accuracy using computed tomography
Bronchoscopy allows direct visualization of trachea and bronchi by rigid open tube bronchoscope or flexible fiber optic scope Detailed evaluation of airways with bronchoscopy offers advantages over other diagnostic tools and allows interventional procedures such as biopsy of lesions removal of foreign bodies dilatations of stenosis and obtaining samples for cytological and microbiologic analysis
Bronchoscopy can be performed either by rigid or flexible instruments depending on the needs of patients The pediatric airway is notably different from adults It is smaller in size larynx and tracheal proportion is more as compared to adults and epiglottis is more posterior and narrower
Fiber Optic bronchoscopy with or without bronchoalveolar lavage is particularly important in the diagnosis and treatment of specific respiratory problems in critically ill infants and children hospitalized in the pediatric Intensive care unitThese comprise situations such as segmental lung collapse pulmonary infections including community-acquired and ventilator-associated pneumonia pulmonary infections in immunocompromised hosts and pulmonary bleeding In addition bronchscopy has a special role in airway problems in very sick pediatric patients It may be crucial in intubation of the difficult airways and in the assessment of airway anomalies
There are various indications for bronchoscopy persistent stridor congenital anatomical or acquired anomalies persistent wheezing hemoptysis persistent or recurring atelectasis persistent or recurring pneumonia and localized hyperinflation Other uses of bronchoscopy are bronchoalveolar lavage getting biopsy samples and aspiration of secretions Examples of therapeutic bronchoscopy are administering medications and removing foreign bodies
Absolute contraindications for bronchoscopy include severe hypoxemia hemodynamic instability and uncorrected hemorrhagic diathesis Severe pulmonary hypertension and congenital cyanotic cardiomyopathy with increased bronchial collateral circulation are relative contraindications In addition instabilities in the cervical spine or atlanto occipital transition are considered relative contraindications for rigid bronchoscopy
The common complication of bronchoscopy is related to anesthesia mechanical trauma epistaxis pneumothorax and hemoptysis hypoxemia laryngospasm post-lavage fever and infection
The laryngotracheal and bronchial airway is affected by a wide range of diseases and imaging is essential for assessing these anomalies The location scope and type of these lesions may be determined with great accuracy using computed tomography
Bronchoscopy allows direct visualization of trachea and bronchi by rigid open tube bronchoscope or flexible fiber optic scope Detailed evaluation of airways with bronchoscopy offers advantages over other diagnostic tools and allows interventional procedures such as biopsy of lesions removal of foreign bodies dilatations of stenosis and obtaining samples for cytological and microbiologic analysis
Bronchoscopy can be performed either by rigid or flexible instruments depending on the needs of patients The pediatric airway is notably different from adults It is smaller in size larynx and tracheal proportion is more as compared to adults and epiglottis is more posterior and narrower
Fiber Optic bronchoscopy with or without bronchoalveolar lavage is particularly important in the diagnosis and treatment of specific respiratory problems in critically ill infants and children hospitalized in the pediatric Intensive care unitThese comprise situations such as segmental lung collapse pulmonary infections including community-acquired and ventilator-associated pneumonia pulmonary infections in immunocompromised hosts and pulmonary bleeding In addition bronchscopy has a special role in airway problems in very sick pediatric patients It may be crucial in intubation of the difficult airways and in the assessment of airway anomalies
There are various indications for bronchoscopy persistent stridor congenital anatomical or acquired anomalies persistent wheezing hemoptysis persistent or recurring atelectasis persistent or recurring pneumonia and localized hyperinflation Other uses of bronchoscopy are bronchoalveolar lavage getting biopsy samples and aspiration of secretions Examples of therapeutic bronchoscopy are administering medications and removing foreign bodies
Absolute contraindications for bronchoscopy include severe hypoxemia hemodynamic instability and uncorrected hemorrhagic diathesis Severe pulmonary hypertension and congenital cyanotic cardiomyopathy with increased bronchial collateral circulation are relative contraindications In addition instabilities in the cervical spine or atlanto occipital transition are considered relative contraindications for rigid bronchoscopy
The common complication of bronchoscopy is related to anesthesia mechanical trauma epistaxis pneumothorax and hemoptysis hypoxemia laryngospasm post-lavage fever and infection
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None