Ignite Creation Date:
2024-10-25 @ 8:02 PM
Last Modification Date:
2024-10-26 @ 3:35 PM
Study NCT ID:
NCT06516770
Status:
ENROLLING_BY_INVITATION
Last Update Posted:
None
First Post:
2024-07-08
Brief Title:
Movement Control and Motor Unit Behavior Responses to Different Types of Stimulation
Sponsor:
None
Organization:
None
Study Overview
Official Title:
The Effects of Different Types of Stimulation on Movement Control and Motor Unit Behavior in Individuals With Lumbopelvic Movement Control Impairment
Status:
ENROLLING_BY_INVITATION
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study aims to determine the effect of different stimulations including 1 transcranial direct current stimulation tDCS 2 neuromuscular electrical stimulation NMES 3 motor control exercise MCE and 4 isometric exercise IE on movement control and motor unit behavior in individuals with movement control impairment and determine the correlation between movement control and motor unit behavior
Detailed Description:
After obtaining the written informed consent all participants will fill out the information sheet for demographic data Data collection will be conducted in private laboratory with closed environment Only lab staffs can access to the lab Female researchers will perform participant preparation Participants will be informed that they have to change their cloth to lab tank top to expose their lower back area However they can decline to change their cloth In this case researchers will fold their cloth to expose the lower back The body landmarks will be identified These landmarks include 1 spinous processes L1 and S1 levels 2 lumbar multifidus LM 2 cm lateral to lower half of L4 spinous process 3 bilateral lateral epicondyle of femur and 4 bilateral lateral malleolus Spinous process of L1 S2 bilateral lateral epicondyle of femur and bilateral lateral malleolus will be used as locations for inertial measurement unit IMU sensors while LM location will be used to place surface electrode for decomposition electromyography dEMG This preparation process will take about 20 minutes
The participant will be asked to perform 1-minute active forward bend based on speed and load that can differentiate between healthy individuals and individuals with movement control impairment IMU and dEMG data are concurrently collected Five-minute rest will be provided to avoid muscle fatigue After that participant will be randomly assigned to one of four stimulations including transcranial direct current stimulation tDCS neuromuscular electrical stimulation NMES isometric exercise IE and motor control exercise MCE Each stimulation will take approximately 20 minutes
Types of stimulation Transcranial direct current stimulation tDCS The participant will receive the tDCS using 5X7 cm electrodes The anodal electrode will be placed on M1 representing the back muscles 1 cm anterior and 4 cm lateral to the vertex while cathodal electrode will be placed on contralateral supraorbital area The intensity will be set at 2 mA with 10-second fade inout The subject will be stimulated by tDCS for 20 minutes
Neuromuscular electrical stimulation NMES The participants will receive the NMES using interferential mode 6000 Hz beat frequency 20-50 Hz scanning effect on bilateral LM The intensity will be set at the subjects maximum tolerance Stimulation will be set at 10 seconds on and 60 seconds off to minimize muscle fatigue The total NMES time is 20 minutes
Isometric exercise IE The participant will be instructed to perform isometric back extension exercise in modified Sorensen position The participant will hold 60 seconds in neutral position for 5 repetitions with 3 minutes rest between repetitions
Movement control exercise MCE The participant will be instructed to perform co-contraction of transverse abdominis and lumbar multifidus muscle while performing self-selected pace forward bend Emphasis will be given to move in control manner smooth and symmetrical movement The participant will perform 4 minutes of continuous movement for 4 sets with 1 minute rest between sets This exercise is low intensity focusing on control of movement therefore the occurrence of muscle fatigue is unlikely
After completion of one session stimulation the participant will be asked to perform 1-minute active forward bend with the same speed and load again while IMU and dEMG data will be simultaneously corrected IMU data will be used to determine the effect of stimulation tDCS NMES IE and MCE on movement control in individuals with movement control impairment dEMG data will be used to determine the effect of each stimulation on motor unit behavior spatial and temporal motor unit recruitment In addition IMU and dEMG data will be further used to determine the association between movement control and motor unit behavior Data collection including 20-minute stimulation will take approximately 30 minutes
The participant will be asked to perform 1-minute active forward bend based on speed and load that can differentiate between healthy individuals and individuals with movement control impairment IMU and dEMG data are concurrently collected Five-minute rest will be provided to avoid muscle fatigue After that participant will be randomly assigned to one of four stimulations including transcranial direct current stimulation tDCS neuromuscular electrical stimulation NMES isometric exercise IE and motor control exercise MCE Each stimulation will take approximately 20 minutes
Types of stimulation Transcranial direct current stimulation tDCS The participant will receive the tDCS using 5X7 cm electrodes The anodal electrode will be placed on M1 representing the back muscles 1 cm anterior and 4 cm lateral to the vertex while cathodal electrode will be placed on contralateral supraorbital area The intensity will be set at 2 mA with 10-second fade inout The subject will be stimulated by tDCS for 20 minutes
Neuromuscular electrical stimulation NMES The participants will receive the NMES using interferential mode 6000 Hz beat frequency 20-50 Hz scanning effect on bilateral LM The intensity will be set at the subjects maximum tolerance Stimulation will be set at 10 seconds on and 60 seconds off to minimize muscle fatigue The total NMES time is 20 minutes
Isometric exercise IE The participant will be instructed to perform isometric back extension exercise in modified Sorensen position The participant will hold 60 seconds in neutral position for 5 repetitions with 3 minutes rest between repetitions
Movement control exercise MCE The participant will be instructed to perform co-contraction of transverse abdominis and lumbar multifidus muscle while performing self-selected pace forward bend Emphasis will be given to move in control manner smooth and symmetrical movement The participant will perform 4 minutes of continuous movement for 4 sets with 1 minute rest between sets This exercise is low intensity focusing on control of movement therefore the occurrence of muscle fatigue is unlikely
After completion of one session stimulation the participant will be asked to perform 1-minute active forward bend with the same speed and load again while IMU and dEMG data will be simultaneously corrected IMU data will be used to determine the effect of stimulation tDCS NMES IE and MCE on movement control in individuals with movement control impairment dEMG data will be used to determine the effect of each stimulation on motor unit behavior spatial and temporal motor unit recruitment In addition IMU and dEMG data will be further used to determine the association between movement control and motor unit behavior Data collection including 20-minute stimulation will take approximately 30 minutes
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None