Ignite Creation Date:
2024-10-25 @ 8:02 PM
Last Modification Date:
2024-10-26 @ 3:38 PM
Study NCT ID:
NCT06559761
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-08-06
Brief Title:
Image Driven Hepatocellular Carcinoma Invasiveness Evaluation Research
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Image Driven Hepatocellular Carcinoma Invasiveness Evaluation Research
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Hepatocellular carcinoma HCC is a highly heterogeneous malignant tumor with significant differences in invasion proliferation ability and patient prognosis Currently there is a lack of non-invasive and simple indicators to predict the prognosis of HCC patients and assist clinical decision-making The identification of HCC macroscopic or histopathological classification requires large pathological specimens obtained through surgical resection but only about 20 of patients are eligible for surgical treatment Moreover most liver cancer diagnoses can be confirmed by imaging examinations without relying on pathological results For patients who have not undergone surgical resection the lack of histopathological information during treatment means that there is no basis for judging tumor proliferation and obtaining rich prognostic information Therefore evaluating the invasion and proliferation ability of HCC based on macroscopic imaging assessment has important implications for guiding individualized diagnosis and treatment throughout the entire process including surgical strategy guidance local treatment selection systemic therapy planning as well as patient follow-up and prognosis evaluation
Ultrasound and MRI are ideal entry points as first-line imaging methods for liver cancer diagnosis This study aims to evaluate HCC macroscopic or histopathological classification based on multimodal imaging ultrasound CT MRI thereby assessing its invasion and proliferation ability which has important implications for guiding individualized diagnosis and treatment throughout the entire process including surgical strategy guidance local treatment selection systemic therapy planning as well as patient follow-up and prognosis evaluation
By analyzing macroscopic image features we aim to explore their cross-scale correlations with HCC macroscopic classificationhistopathological classificationand gene molecular typing
Ultrasound and MRI are ideal entry points as first-line imaging methods for liver cancer diagnosis This study aims to evaluate HCC macroscopic or histopathological classification based on multimodal imaging ultrasound CT MRI thereby assessing its invasion and proliferation ability which has important implications for guiding individualized diagnosis and treatment throughout the entire process including surgical strategy guidance local treatment selection systemic therapy planning as well as patient follow-up and prognosis evaluation
By analyzing macroscopic image features we aim to explore their cross-scale correlations with HCC macroscopic classificationhistopathological classificationand gene molecular typing
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None