Ignite Creation Date:
2024-10-25 @ 8:02 PM
Last Modification Date:
2024-10-26 @ 3:40 PM
Study NCT ID:
NCT06591767
Status:
COMPLETED
Last Update Posted:
None
First Post:
2024-09-08
Brief Title:
Quercetin as Possible Supportive Therapy for Mild to Moderate Hyperuricemia
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Potential Pharmacological Effects of Supplemental Quercetin in the Management of Mild to Moderate Hyperuricemia
Status:
COMPLETED
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Uric acid a metabolic byproduct of purine degradation in humans is a known risk factor for conditions such as gout and type 2 diabetes Research has shown that supplementation with quercetin can significantly reduce plasma uric acid levels in individuals with mild hyperuricemia potentially mitigating these associated risks
Detailed Description:
Uric acid a metabolic byproduct of purine degradation in humans is a significant risk factor for the development of gout and type 2 diabetes Supplementation with quercetin a flavonol not naturally produced by the human body has been shown to significantly reduce plasma uric acid levels in individuals with mild hyperuricemia This effect is primarily achieved through the inhibition of xanthine oxidoreductase an enzyme crucial to uric acid production
Quercetin is the most abundant polyphenol found in fruits and vegetables and is widely used as a dietary supplement to boost the immune system and promote overall health It is characterized by three key properties antioxidant anti-inflammatory and immunomodulatory These combined actions make quercetin a promising candidate for supporting various health conditions where oxidative stress inflammation and immune function play a role including cardiovascular health healthy aging bone and joint health sports and physical activity gut health and respiratory well-being
The above-described properties of quercetin prompted investigators to explore its potential uricosuric therapeutic effect in two clinical studies The first study will assess this effect in a retrospective cohort of COVID-19 patients who received quercetin as a supplemental therapy In the second study its potential uricosuric therapeutic effect will be assessed in a randomized controlled prospective clinical trial involving patients with mild to moderate hyperuricemia
Quercetin is the most abundant polyphenol found in fruits and vegetables and is widely used as a dietary supplement to boost the immune system and promote overall health It is characterized by three key properties antioxidant anti-inflammatory and immunomodulatory These combined actions make quercetin a promising candidate for supporting various health conditions where oxidative stress inflammation and immune function play a role including cardiovascular health healthy aging bone and joint health sports and physical activity gut health and respiratory well-being
The above-described properties of quercetin prompted investigators to explore its potential uricosuric therapeutic effect in two clinical studies The first study will assess this effect in a retrospective cohort of COVID-19 patients who received quercetin as a supplemental therapy In the second study its potential uricosuric therapeutic effect will be assessed in a randomized controlled prospective clinical trial involving patients with mild to moderate hyperuricemia
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None