Ignite Creation Date:
2024-10-25 @ 7:58 PM
Last Modification Date:
2024-10-26 @ 3:41 PM
Study NCT ID:
NCT06612567
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-09-22
Brief Title:
Normal Variants and Pitfalls of 18F_FDG PETCT in Pediatric Oncology
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Normal Variants and Pitfalls of 18F_FDG PETCT Imaging in Pediatric Oncology
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Detection Normal variants and pitfalls of 18_F _FDG PETCT imaging in pediatic oncology
Detailed Description:
Although pediatric cancer is relatively rare compared with adult cancer it is the second most common cause of death after injury in children and adolescents lymphoma Leukemia and brain cancer account for more than half of pediatric cancers followed by neuroblastoma soft-tissue sarcomas Wilms tumors and bone tumors
18Fluorine-fluorodeoxyglucose 18F-FDG positron emission tomographycomputed tomography PETCT plays an important role staging restaging response to treatment in childhood malignancies PET-only examinations have been replaced by hybrid systems in the recent decades where PET and CT are used together in oncology In this imaging system PET and CT are used together for functional data and morphological information respectively 2 Although 18F-FDG PETCT is now well established as an accurate method for the staging and restaging of various cancers it is also well recognized that many false-positive results can occur
The normal distribution of FDG uptake in children differs from adults Also even though FDG is used widely in oncology it is not tumor specific Uptake of FDG may be seen in numerous benign conditions including inflammation infection and trauma Proper interpretation of pediatric FDG PETCT studies requires knowledge of the normal distribution of FDG uptake in children and an insight into the physiologic variants benign lesions and PETCT related artifacts
By understanding the potential causes of misinterpretation we can increase the accuracy of interpretation decrease the number of unnecessary follow-up studies and improve treatment outcome
18Fluorine-fluorodeoxyglucose 18F-FDG positron emission tomographycomputed tomography PETCT plays an important role staging restaging response to treatment in childhood malignancies PET-only examinations have been replaced by hybrid systems in the recent decades where PET and CT are used together in oncology In this imaging system PET and CT are used together for functional data and morphological information respectively 2 Although 18F-FDG PETCT is now well established as an accurate method for the staging and restaging of various cancers it is also well recognized that many false-positive results can occur
The normal distribution of FDG uptake in children differs from adults Also even though FDG is used widely in oncology it is not tumor specific Uptake of FDG may be seen in numerous benign conditions including inflammation infection and trauma Proper interpretation of pediatric FDG PETCT studies requires knowledge of the normal distribution of FDG uptake in children and an insight into the physiologic variants benign lesions and PETCT related artifacts
By understanding the potential causes of misinterpretation we can increase the accuracy of interpretation decrease the number of unnecessary follow-up studies and improve treatment outcome
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None