Ignite Creation Date:
2024-05-05 @ 7:07 PM
Last Modification Date:
2024-10-26 @ 9:42 AM
Study NCT ID:
NCT00600561
Status:
COMPLETED
Last Update Posted:
2008-01-25
First Post:
2008-01-14
Brief Title:
Mindfulness Meditation Training in HIV
Sponsor:
University of California Los Angeles
Organization:
University of California Los Angeles
Study Overview
Official Title:
Biobehavioral Effects of Mindfulness-Based Stress Reduction in HIV
Status:
COMPLETED
Status Verified Date:
2008-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
MBSR
Brief Summary:
The purpose of this study is to investigate whether Mindfulness-Based Stress Reduction MBSR vs a one-day MBSR seminar improves immune CD4 T lymphocytes and virological HIV viral load status in HIV-1 infected adults The secondary goal of the study is to determine if MBSR vs a one-day MBSR seminar improves self-reported HIV-related quality of life
Detailed Description:
Mindfulness meditation which is described as a process of bringing awareness to moment-to-moment experience has been receiving substantial scientific attention as a process that can be stress and health protective Brown Ryan Creswell 2007 Recent reviews by Baer 2003 Bishop 2002 and Grossman et al 2004 support the effectiveness of the standardized and manualized MBSR program in reducing stress and functional disability in a variety of chronic illnesses although no studies have tested if MBSR impacts clinical markers of HIV although some evidence suggests that MBSR improves some markers of innate immunity and quality of life in HIV-infected adults see Robinson Mathews Witek-Janusek 2003 In this study we propose to extend this work by investigating the impact of this intervention on biological and functional health status in HIV-positive adults
We propose to determine whether the 8-week MBSR program is more effective than a one-day MBSR seminar in 1 maintaining immune resistance in HIV infection ie maintaining counts of CD4 T lymphocytes and reducing HIV viral load and 2 improving HIV-related quality of life Additional analyses will test for a dose-response effect of MBSR by examining if MBSR class attendance and daily meditation practice are associated with the primary and secondary outcomes These aims will be tested in a sample of 50 HIV-positive adults that is diverse with respect to ethnicity gender and sexual orientation
We propose to determine whether the 8-week MBSR program is more effective than a one-day MBSR seminar in 1 maintaining immune resistance in HIV infection ie maintaining counts of CD4 T lymphocytes and reducing HIV viral load and 2 improving HIV-related quality of life Additional analyses will test for a dose-response effect of MBSR by examining if MBSR class attendance and daily meditation practice are associated with the primary and secondary outcomes These aims will be tested in a sample of 50 HIV-positive adults that is diverse with respect to ethnicity gender and sexual orientation
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| M01RR000865 | NIH | None | httpsreporternihgovquickSearchM01RR000865 |