Ignite Creation Date:
2024-10-25 @ 7:57 PM
Last Modification Date:
2024-10-26 @ 3:39 PM
Study NCT ID:
NCT06590818
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-09-01
Brief Title:
The Effect of Body Mass Index on Short-term Results of HTO
Sponsor:
None
Organization:
None
Study Overview
Official Title:
The Effect of Body Mass Index on Short-term Results of HTO for Treatment of OA With Varus Knee in Upper Egypt Population
Status:
RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The knee joint plays a major role in weight transmission of the body in day-to-day activities The biomechanics of the knee and malalignment in lower limb anatomy are major risk factors for chronic knee pain leaving Total Knee Arthroplasty TKA as the best and most successful option for patients with end-stage osteoarthritis OA
Detailed Description:
Osteoarthritis is a degenerative disease characterized by progressive joint damageThe knee is one of the joints most affected by this pathology and it is estimated that 10 of men and 13 of women older than 60 years present itIt is characterized by pain functional limitation and reduction of quality of life
Knee osteoarthritis KOA is a multi-etiological chronic disabling disease that affects the entire knee joint which is the most common site of involvement in OA KOA is classified as primary or secondary depending on etiology The pathogenesis of primary KOA is complex and involves numerous factors such as mechanical stress inflammation metabolism immunity and genetics with age genetics body weight sex and race being risk factors
Diagnosis of knee osteoarthritis can be confirmed based on clinical andor radiological features The potential of a progressive disease can be prevented or decreased by earlier recognition and correction of associated factorsObesity and alignment especially varus malalignment are recognized factors of a progressive disease Both non pharmalogical as well as pharmacological modalities of treatment are useful in managing the symptoms of knee osteoarthritis Surgery should be considered only in patients who do not respond to medical therapy
Varus knee osteoarthritis is one of the most common knee diseases in clinical practice Knee pain and limited range of motion seriously affect the patients quality of life However there is need for further exploration into the prevention and treatment of postoperative complications following artificial joint replacement
Osteotomy techniques such as high tibial osteotomy are primarily used for the treatment of KOA with varus and valgus deformities
High body mass index is a risk factor for KOA A previous study reported a 35 increase in KOA risk with every 5-unit increase in body mass index This is primarily attributed to the fact that greater body weight increases the weight-bearing pressure of the knee joint thereby increasing the probability of KOA
Knee osteoarthritis KOA is a multi-etiological chronic disabling disease that affects the entire knee joint which is the most common site of involvement in OA KOA is classified as primary or secondary depending on etiology The pathogenesis of primary KOA is complex and involves numerous factors such as mechanical stress inflammation metabolism immunity and genetics with age genetics body weight sex and race being risk factors
Diagnosis of knee osteoarthritis can be confirmed based on clinical andor radiological features The potential of a progressive disease can be prevented or decreased by earlier recognition and correction of associated factorsObesity and alignment especially varus malalignment are recognized factors of a progressive disease Both non pharmalogical as well as pharmacological modalities of treatment are useful in managing the symptoms of knee osteoarthritis Surgery should be considered only in patients who do not respond to medical therapy
Varus knee osteoarthritis is one of the most common knee diseases in clinical practice Knee pain and limited range of motion seriously affect the patients quality of life However there is need for further exploration into the prevention and treatment of postoperative complications following artificial joint replacement
Osteotomy techniques such as high tibial osteotomy are primarily used for the treatment of KOA with varus and valgus deformities
High body mass index is a risk factor for KOA A previous study reported a 35 increase in KOA risk with every 5-unit increase in body mass index This is primarily attributed to the fact that greater body weight increases the weight-bearing pressure of the knee joint thereby increasing the probability of KOA
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None