Ignite Creation Date:
2024-10-25 @ 7:56 PM
Last Modification Date:
2024-10-26 @ 3:37 PM
Study NCT ID:
NCT06551259
Status:
COMPLETED
Last Update Posted:
None
First Post:
2024-08-09
Brief Title:
Effect of Dexmedetomidine on Central Nervous System Complications in Patients Undergoing Cardiac Surgery
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Effect of Intraoperative Dextrometomidine on Complications of the Central Nervous System in Patients Undergoing Cardiac Surgery a Randomized Controlled Trial
Status:
COMPLETED
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
With the continuous improvement of medical technology more and more patients need to undergo surgery as a kind of treatment for their diseases However there are various pains that may occur in the perioperative period risks associated with anesthesia loss of body organs surgical trauma and postoperative procedures Factors such as the onset of the disease can cause the vast majority of patients to have varying degrees of emotional reactions such as worry worry nervousness and fear Emotional disorders such as depressed mood disappointed crying decreased mobility and delayed thinking and cognitive function that is postoperative psychiatric symptoms
Dexmedetomidine DEX is an alpha-2 adrenergic agonist that works by inhibiting norepinephrine Releasing renaline which reduces inflammation and thus plays a protective role in the central nervous system Previous studies have shown that dexmedetomidine is lowering DEX has the potential to prevent and treat patients undergoing cardiac surgery The role of postoperative anxiety and depression needs to be further explored for evidence-based evidence Based on the above research background the hypothesis of this study is proposed The intraoperative use of dexmedetomidine has a positive effect on alleviating postoperative anxiety and depression in patients undergoing postoperative cardiac surgery
Dexmedetomidine DEX is an alpha-2 adrenergic agonist that works by inhibiting norepinephrine Releasing renaline which reduces inflammation and thus plays a protective role in the central nervous system Previous studies have shown that dexmedetomidine is lowering DEX has the potential to prevent and treat patients undergoing cardiac surgery The role of postoperative anxiety and depression needs to be further explored for evidence-based evidence Based on the above research background the hypothesis of this study is proposed The intraoperative use of dexmedetomidine has a positive effect on alleviating postoperative anxiety and depression in patients undergoing postoperative cardiac surgery
Detailed Description:
1 Observing the effect of intraoperative use of dexmedetomidine on the incidence of postoperative anxiety and depression in patients undergoing cardiac surgery
2 Observe the effects of intraoperative use of dexmedetomidine on postoperative delirium quality of life pain scores and sleep quality in patients undergoing cardiac surgery
3 To provide a feasible plan for preventing and treating postoperative anxiety and depression in patients undergoing cardiac surgery improve the quality of patient prognosis and reduce the burden on society
2 Observe the effects of intraoperative use of dexmedetomidine on postoperative delirium quality of life pain scores and sleep quality in patients undergoing cardiac surgery
3 To provide a feasible plan for preventing and treating postoperative anxiety and depression in patients undergoing cardiac surgery improve the quality of patient prognosis and reduce the burden on society
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None