Ignite Creation Date:
2024-10-25 @ 7:56 PM
Last Modification Date:
2024-10-26 @ 3:40 PM
Study NCT ID:
NCT06605144
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-09-10
Brief Title:
Canadian Critical Care Comparative Effectiveness Platform
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Canadian Critical Care Comparative Effectiveness Platforme dÉvaluation Clinique Comparée en Soins Critiques CEPEC
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
CEPEC
Brief Summary:
The Canadian Critical Care Comparative Effectiveness Platforme dÉvaluation Clinique Comparée en soins Critiques CEPEC is an international multi-centered randomized adaptive platform clinical trial CEPEC will evaluate supportive care interventions that are used routinely in intensive care units throughout the world
Detailed Description:
Many supportive therapies used daily in the ICU setting remain under-studied despite being resource-intensive CEPEC aims to incorporate domains evaluating vasopressors platelets nutrition sedation and analgesia and other interventions
The first domain studied will be vasopressors The investigators will investigate whether vasoactive medications should be used differently for different subgroups of patients who are in a state of cardiovascular shock ie heterogeneity of treatment effects Vasoactive medications are common in critically ill patients and have considerable patient hospital and health system resource impact but their use remains poorly supported by scientific evidence
The first domain studied will be vasopressors The investigators will investigate whether vasoactive medications should be used differently for different subgroups of patients who are in a state of cardiovascular shock ie heterogeneity of treatment effects Vasoactive medications are common in critically ill patients and have considerable patient hospital and health system resource impact but their use remains poorly supported by scientific evidence
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None