Ignite Creation Date:
2024-10-25 @ 7:55 PM
Last Modification Date:
2024-10-26 @ 3:42 PM
Study NCT ID:
NCT06628817
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-10-04
Brief Title:
The Intensive Care Bundle with Mortality Reduction in Acute Ischemic Stroke Trial
Sponsor:
None
Organization:
None
Study Overview
Official Title:
The Intensive Care Bundle with Mortality Reduction in Acute Ischemic Stroke Trial
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
ICB-MRAIS
Brief Summary:
Ischemic stroke also known as cerebral infarction accounts for as high as 60 to 80 of all stroke cases and it is characterized by high morbidity high disability rate and high mortality rate In recent years acute ischemic stroke AIS has risen to the top of the list of causes of death in Chinese people bringing a heavy burden on families society and the country In the process of continuous accumulation of evidence-based evidence the management of stroke has gradually become systematic and the demand for multi-disciplinary collaboration has become increasingly prominent thus the concept of organized medical care has emerged
Improving the prognosis of stroke faces multiple challenges including timely identification of stroke patients intravenous thrombolysis after clinical doctors evaluate indications and contraindications reducing in-hospital stroke complications accurately diagnosing the cause of stroke and implementing precise prevention In the past there were relatively few clinical trials on reducing mortality The 2023 Dutch PRECIOUS study used metoclopramide ceftriaxone and acetaminophen to prevent aspiration infection and fever in elderly patients with acute stroke The results showed that there was no significant difference in acute 90-day good functional outcomes and reduced mortality The INTERACT3 trial results showed that for patients with acute cerebral hemorrhage compared with conventional medical care the use of a new combination management plan namely early intensive blood pressure management strict control of blood sugar elevation body temperature control and anticoagulation therapy can significantly reduce the risk of 6-month adverse functional prognosis in patients improve the survival rate and quality of life of patients and the possibility of patients being discharged within 7 days Therefore the use of a new combination management plan including improving the efficiency of reperfusion therapy reducing the occurrence of stroke complications and carrying out precise etiological treatment may reduce the mortality rate of patients
The Zhejiang Stroke Online Platform can monitor the comprehensive information of treatment and management in the process of clinical doctors receiving AIS patients in real time According to the self-feedback of each unit of the online platform the provincial center conducts multi-level new combined management intervention on it The purpose of this study is to explore whether the new combined management intervention measures can reduce the mortality rate of AIS patients on the basis of the implementation of stroke online platform monitoring
Improving the prognosis of stroke faces multiple challenges including timely identification of stroke patients intravenous thrombolysis after clinical doctors evaluate indications and contraindications reducing in-hospital stroke complications accurately diagnosing the cause of stroke and implementing precise prevention In the past there were relatively few clinical trials on reducing mortality The 2023 Dutch PRECIOUS study used metoclopramide ceftriaxone and acetaminophen to prevent aspiration infection and fever in elderly patients with acute stroke The results showed that there was no significant difference in acute 90-day good functional outcomes and reduced mortality The INTERACT3 trial results showed that for patients with acute cerebral hemorrhage compared with conventional medical care the use of a new combination management plan namely early intensive blood pressure management strict control of blood sugar elevation body temperature control and anticoagulation therapy can significantly reduce the risk of 6-month adverse functional prognosis in patients improve the survival rate and quality of life of patients and the possibility of patients being discharged within 7 days Therefore the use of a new combination management plan including improving the efficiency of reperfusion therapy reducing the occurrence of stroke complications and carrying out precise etiological treatment may reduce the mortality rate of patients
The Zhejiang Stroke Online Platform can monitor the comprehensive information of treatment and management in the process of clinical doctors receiving AIS patients in real time According to the self-feedback of each unit of the online platform the provincial center conducts multi-level new combined management intervention on it The purpose of this study is to explore whether the new combined management intervention measures can reduce the mortality rate of AIS patients on the basis of the implementation of stroke online platform monitoring
Detailed Description:
Ischemic stroke also known as cerebral infarction accounts for as high as 60 to 80 of all stroke cases and it is characterized by high morbidity high disability rate and high mortality rate In recent years acute ischemic stroke AIS has risen to the top of the list of causes of death in Chinese people bringing a heavy burden on families society and the country In the process of continuous accumulation of evidence-based evidence the management of stroke has gradually become systematic and the demand for multi-disciplinary collaboration has become increasingly prominent thus the concept of organized medical care has emerged
Improving the prognosis of stroke faces multiple challenges including timely identification of stroke patients intravenous thrombolysis after clinical doctors evaluate indications and contraindications reducing in-hospital stroke complications accurately diagnosing the cause of stroke and implementing precise prevention In the past there were relatively few clinical trials on reducing mortality The 2023 Dutch PRECIOUS study used metoclopramide ceftriaxone and acetaminophen to prevent aspiration infection and fever in elderly patients with acute stroke The results showed that there was no significant difference in acute 90-day good functional outcomes and reduced mortality The INTERACT3 trial results showed that for patients with acute cerebral hemorrhage compared with conventional medical care the use of a new combination management plan namely early intensive blood pressure management strict control of blood sugar elevation body temperature control and anticoagulation therapy can significantly reduce the risk of 6-month adverse functional prognosis in patients improve the survival rate and quality of life of patients and the possibility of patients being discharged within 7 days Therefore the use of a new combination management plan including improving the efficiency of reperfusion therapy reducing the occurrence of stroke complications and carrying out precise etiological treatment may reduce the mortality rate of patients
The Zhejiang Stroke Online Platform can monitor the comprehensive information of treatment and management in the process of clinical doctors receiving AIS patients in real time According to the self-feedback of each unit of the online platform the provincial center conducts multi-level new combined management intervention on it The purpose of this study is to explore whether the new combined management intervention measures can reduce the mortality rate of AIS patients on the basis of the implementation of stroke online platform monitoring
Improving the prognosis of stroke faces multiple challenges including timely identification of stroke patients intravenous thrombolysis after clinical doctors evaluate indications and contraindications reducing in-hospital stroke complications accurately diagnosing the cause of stroke and implementing precise prevention In the past there were relatively few clinical trials on reducing mortality The 2023 Dutch PRECIOUS study used metoclopramide ceftriaxone and acetaminophen to prevent aspiration infection and fever in elderly patients with acute stroke The results showed that there was no significant difference in acute 90-day good functional outcomes and reduced mortality The INTERACT3 trial results showed that for patients with acute cerebral hemorrhage compared with conventional medical care the use of a new combination management plan namely early intensive blood pressure management strict control of blood sugar elevation body temperature control and anticoagulation therapy can significantly reduce the risk of 6-month adverse functional prognosis in patients improve the survival rate and quality of life of patients and the possibility of patients being discharged within 7 days Therefore the use of a new combination management plan including improving the efficiency of reperfusion therapy reducing the occurrence of stroke complications and carrying out precise etiological treatment may reduce the mortality rate of patients
The Zhejiang Stroke Online Platform can monitor the comprehensive information of treatment and management in the process of clinical doctors receiving AIS patients in real time According to the self-feedback of each unit of the online platform the provincial center conducts multi-level new combined management intervention on it The purpose of this study is to explore whether the new combined management intervention measures can reduce the mortality rate of AIS patients on the basis of the implementation of stroke online platform monitoring
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None