Ignite Creation Date:
2024-10-25 @ 7:54 PM
Last Modification Date:
2024-10-26 @ 3:42 PM
Study NCT ID:
NCT06628544
Status:
COMPLETED
Last Update Posted:
None
First Post:
2024-09-27
Brief Title:
Trained Immunity in Fungal Infection and Its Mechanism
Sponsor:
None
Organization:
None
Study Overview
Official Title:
The Role of Trained Immunity in Fungal Infection and the Mechanism Behind it
Status:
COMPLETED
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Investigator vaccinated 76 healthy BCG-naive participant with BCG while 3 participants received Half of BCG-vaccinated participants n 38 received an incremental dose of metformin for 6 days up to 1000 mg twice daily on day 6 On the day 0 total 20 n 10 for BCG vaccination n 10 for BCG vaccination plus taking metformin day 14 total 30 n15 for BCG vaccination n 15 for BCG vaccination plus taking metformin day 90 total 26 n 13 for BCG vaccination n13 for BCG vaccination plus taking metformin of BCG vaccination PBMCs were isolated restimulated with C albicans or Mycobacterium tuberculosis
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None