Ignite Creation Date:
2024-10-25 @ 7:53 PM
Last Modification Date:
2024-10-26 @ 3:39 PM
Study NCT ID:
NCT06581679
Status:
COMPLETED
Last Update Posted:
None
First Post:
2024-08-29
Brief Title:
Adenomyosis and Pregnancy Levonorgestrel vs GnRH for Blastocyst Transfer
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Treatment of Infertile Adenomyosis Patients Using Levonorgestrel-releasing Intrauterine System or Gonadotropin-releasing Hormone Agonist Before Frozen Blastocyst Transfer Improves Manifestations and Increases the Chances of Pregnancy
Status:
COMPLETED
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Adenomyosis is a condition where endometrial tissue grows into the uterine muscle causing symptoms like pelvic pain heavy bleeding and infertility This abnormal growth can lead to a variety of reproductive issues including a higher risk of miscarriage and early pregnancy loss
While there are treatments available for adenomyosis they are often limited due to the lack of precise diagnostic criteria One common approach is the use of gonadotropin-releasing hormone agonist GnRHa which can improve pregnancy rates in infertile women with adenomyosis However its important to note that GnRHa may not restore pregnancy rates to baseline levels
Another potential treatment option is the levonorgestrel-releasing intrauterine system LNG-IUS This device releases a hormone called levonorgestrel into the uterus which can help control the symptoms of endometriosis and adenomyosis Studies have shown that the endometrial concentration of levonorgestrel from the LNG-IUS is significantly higher than in other tissues like the myometrium fallopian tubes and fat tissue
While there are treatments available for adenomyosis they are often limited due to the lack of precise diagnostic criteria One common approach is the use of gonadotropin-releasing hormone agonist GnRHa which can improve pregnancy rates in infertile women with adenomyosis However its important to note that GnRHa may not restore pregnancy rates to baseline levels
Another potential treatment option is the levonorgestrel-releasing intrauterine system LNG-IUS This device releases a hormone called levonorgestrel into the uterus which can help control the symptoms of endometriosis and adenomyosis Studies have shown that the endometrial concentration of levonorgestrel from the LNG-IUS is significantly higher than in other tissues like the myometrium fallopian tubes and fat tissue
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None