Ignite Creation Date:
2025-12-24 @ 7:47 PM
Ignite Modification Date:
2025-12-25 @ 5:24 PM
Study NCT ID:
NCT07302503
Status:
RECRUITING
Last Update Posted:
2025-12-24
First Post:
2025-12-10
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Pilot Study Evaluating brainQuant's Ability to Detect Alterations in White Matter in Diffusion MRI, Indicative of Post-traumatic Lesions
Sponsor:
University Hospital, Strasbourg, France
Organization:
Study Overview
Official Title:
Pilot Study Evaluating brainQuant's Ability to Detect Alterations in White Matter in Diffusion MRI, Indicative of Post-traumatic Lesions
Status:
RECRUITING
Status Verified Date:
2025-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
BQ TC-foot
Brief Summary:
Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease described in boxing, but also in contact sports such as American football.
Soccer, due to repeated headers, could also be associated, albeit to a lesser degree, with the development of this type of pathology.
Indeed, it has been shown that playing soccer can be accompanied by cognitive impairments, and neurodegenerative brain abnormalities have been described in neuropathology studies of former professional soccer players. Subradiological brain abnormalities have been found in multimodal MRI in various sports. Similarly, a decrease in cognitive performance has been described.
The discovery of this type of anomaly in a population of professional footballers nearing the end of their careers could lead to:
* The implementation of appropriate monitoring for professional footballers through early detection of lesions via MRI and cognitive disorders
* The implementation of preventative measures for professional footballers, but also for amateur footballers from a very young age.
Soccer, due to repeated headers, could also be associated, albeit to a lesser degree, with the development of this type of pathology.
Indeed, it has been shown that playing soccer can be accompanied by cognitive impairments, and neurodegenerative brain abnormalities have been described in neuropathology studies of former professional soccer players. Subradiological brain abnormalities have been found in multimodal MRI in various sports. Similarly, a decrease in cognitive performance has been described.
The discovery of this type of anomaly in a population of professional footballers nearing the end of their careers could lead to:
* The implementation of appropriate monitoring for professional footballers through early detection of lesions via MRI and cognitive disorders
* The implementation of preventative measures for professional footballers, but also for amateur footballers from a very young age.
Detailed Description:
None
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: