Ignite Creation Date:
2024-10-25 @ 7:50 PM
Last Modification Date:
2024-10-26 @ 3:42 PM
Study NCT ID:
NCT06628895
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
None
First Post:
2024-09-26
Brief Title:
Effect of Modified Poco-Poco Exercise to Frailty Stages Expression of Global DNA Methylation GDF15 and Lamin A COP
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Effect of Modified Poco-Poco Exercise to Frailty Stages Expression of Global DNA Methylation GDF15 and Lamin A COP on Elderly Living On Community in Bandung
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this clinical trial is to know the effect of multicomponent exercise in frail elderly in community to aging hallmarks The main questions it aims to answer are
1 Do global DNA methylation levels change in elderly people in Bandung after receiving modified poco-poco exercise
2 Do GDF15 levels change in elderly people in Bandung after they are given modified poco-poco exercise
3 Do lamin A COP levels change in elderly people in Bandung after they are given modified poco-poco exercise
4 Does the level of frailty in elderly people in Bandung change after they are given modified poco-poco exercise
Participants will be asked to do flexibility balance aerobic and strengthening exercise included in poco-poco modified exercise three times a week for 12 weeks
1 Do global DNA methylation levels change in elderly people in Bandung after receiving modified poco-poco exercise
2 Do GDF15 levels change in elderly people in Bandung after they are given modified poco-poco exercise
3 Do lamin A COP levels change in elderly people in Bandung after they are given modified poco-poco exercise
4 Does the level of frailty in elderly people in Bandung change after they are given modified poco-poco exercise
Participants will be asked to do flexibility balance aerobic and strengthening exercise included in poco-poco modified exercise three times a week for 12 weeks
Detailed Description:
The elderly population in West Java Province with the age category of 60-64 years is 176 million people Experts estimate that 252 of the Indonesian population experiences frailty Frailty can lead to a variety of worsening health conditions The frailty process is thought to stem from the failure of various mechanisms associated with markers of aging Markers of aging are divided into three categories primary antagonistic and integrative Biomarkers representing these three categories are global DNA methylation GDF15 and Lamin A COP Multicomponent exercise is the most effective intervention in elderly with frailty Elderly people in West Java on average only have an education equivalent to junior high school SMP so activities that promote physical activity are better focused on health activities in the community The poco-poco exercise that is currently commonly practiced almost fulfills the rules of multicomponent exercise for frailty elderly but poco-poco exercise does not have a muscle strengthening exercise component so a modified poco-pcoco exercise was created to fulfill this method
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None