Ignite Creation Date:
2024-10-25 @ 7:49 PM
Last Modification Date:
2024-10-26 @ 3:38 PM
Study NCT ID:
NCT06565403
Status:
COMPLETED
Last Update Posted:
None
First Post:
2024-08-19
Brief Title:
Hyperlactatemia in Critically Ill Patients With Acute Kidney Injury
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Treatment of Critically Ill Patients With Acute Kidney Injury and Dialysis in the Intensive Care Unit
Status:
COMPLETED
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of the research is to determine the prevalence of patients with acute kidney injury in the intensive care unit the role of dialysis treatment in the treatment of these patients
Detailed Description:
A retrospective and observational study was conducted in which the investigators included participants who were hospitalised in the Department of Internal Intensive Care Medicine at the University Hospital Maribor and who required replacement haemodialysis treatment during their hospital stay The decision on haemodialysis treatment was made after an agreement between the attending specialist in intensive care medicine and the nephrologist if there was a clear indication for starting replacement haemodialysis treatment It should be emphasised that each of the patients received an appropriate form of treatment according to indication and clinical condition in line with all relevant recommendations and guidelines
The investigators collected data on the underlying comorbidities the indication for ICU treatment the indication for starting haemodialysis treatment the type of haemodialysis continuous venovenous haemodialysis continuous venovenous haemodiafiltration and the basic parameters of haemodialysis level of ultrafiltration and total ultrafiltration anticoagulants used duration of procedures complications during haemodialysis prescribed and achieved haemodialysis dose with emphasis on the amount of dialysatesubstituteultrafiltrate used Qe effluent dose number of haemodialysis procedures dialysis membrane used with or without immunoadsorbent membrane The investigators collected data on laboratory results haemoglobin leucocytes platelets C-reactive protein procalcitonin lactate urea creatinine bilirubin albumin partial pressure of oxygen in arterial blood myoglobin lactate dehydrogenase Interleukin-6 beta-2-microglobulin cystatin C some measured haemodynamicvital parameters mean arterial pressure diuresis oxygen demand and the dose of vasopressor drugs during treatment The investigators analysed all the data obtained and attempted to objectively evaluate the success of the treatment The investigators compared different haemodialysis membranes standard membranes for continuous haemodialysis vs newer membranes such as Emic-2 and Oxiris membrane different dialysis techniques haemodialysis vs haemodiafiltration and the effects of using the Cytosorb immunoadsorptive membrane The investigators have obtained data on the duration of hospitalisation and survival of participants after treatment up to 1 year
We analysed the data using basic statistical methods where a value of p 005 is considered statistically significant
The investigators collected data on the underlying comorbidities the indication for ICU treatment the indication for starting haemodialysis treatment the type of haemodialysis continuous venovenous haemodialysis continuous venovenous haemodiafiltration and the basic parameters of haemodialysis level of ultrafiltration and total ultrafiltration anticoagulants used duration of procedures complications during haemodialysis prescribed and achieved haemodialysis dose with emphasis on the amount of dialysatesubstituteultrafiltrate used Qe effluent dose number of haemodialysis procedures dialysis membrane used with or without immunoadsorbent membrane The investigators collected data on laboratory results haemoglobin leucocytes platelets C-reactive protein procalcitonin lactate urea creatinine bilirubin albumin partial pressure of oxygen in arterial blood myoglobin lactate dehydrogenase Interleukin-6 beta-2-microglobulin cystatin C some measured haemodynamicvital parameters mean arterial pressure diuresis oxygen demand and the dose of vasopressor drugs during treatment The investigators analysed all the data obtained and attempted to objectively evaluate the success of the treatment The investigators compared different haemodialysis membranes standard membranes for continuous haemodialysis vs newer membranes such as Emic-2 and Oxiris membrane different dialysis techniques haemodialysis vs haemodiafiltration and the effects of using the Cytosorb immunoadsorptive membrane The investigators have obtained data on the duration of hospitalisation and survival of participants after treatment up to 1 year
We analysed the data using basic statistical methods where a value of p 005 is considered statistically significant
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None